Odoratisol C

Base Information

Chemical Name:Odoratisol C
CAS No.:891182-95-9
Molecular Formula:C₂₀H₂₄O₅
Molecular Weight:344.408
Hs Code.:
Nikkaji Number:J259.873F
Wikidata:Q105012226

Synonyms:Odoratisol C;(-)-Verrucosin;(-)-Odoratisol C;891182-95-9;Phenol, 4,4'-((2R,3R,4R,5S)-tetrahydro-3,4-dimethyl-2,5-furandiyl)bis(2-methoxy-

Suppliers and Price of Odoratisol C

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Odoratisol C

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:344.16237386
Heavy Atom Count:25
Complexity:392

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C(C(OC1C2=CC(=C(C=C2)O)OC)C3=CC(=C(C=C3)O)OC)C
Isomeric SMILES:C[C@@H]1[C@H]([C@H](O[C@H]1C2=CC(=C(C=C2)O)OC)C3=CC(=C(C=C3)O)OC)C

Technology Process of Odoratisol C

There total 24 articles about Odoratisol C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: (7S,7'R,8R,8'R)-4,4'-dibenzyloxy-3,3'-dimethoxy-7,7'-epoxylignane

: 891182-95-9
(7R,8R,7'S,8'R)-4-hydroxy-3-methoxy-4'-hydroxy-3'-methoxy-7,7'-epoxylignan

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; at 20 ℃; for 5h;
DOI:10.1271/bbb.70275

Reference yield:

: C₂₆H₃₈O₅Si

: 891182-95-9
(7R,8R,7'S,8'R)-4-hydroxy-3-methoxy-4'-hydroxy-3'-methoxy-7,7'-epoxylignan

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h;
DOI:10.1021/ol7016388

Reference yield:

: 954114-86-4
(3R,4R,5S)-5-(4-(benzyloxy)-3-methoxyphenyl)-3,4-dimethyldihydrofuran-2(3H)-one

: 891182-95-9
(7R,8R,7'S,8'R)-4-hydroxy-3-methoxy-4'-hydroxy-3'-methoxy-7,7'-epoxylignan

Guidance literature:: Multi-step reaction with 4 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C

1.2: 70 percent / tetrahydrofuran; hexane / 0.5 h / -78 °C

2.1: BF₃*Et₂O / CH₂Cl₂ / 2 h / -78 - -20 °C

2.2: 18 percent / NaBH₃CN / CH₂Cl₂; acetonitrile / 0.5 h / -78 °C

3.1: hydrogen / Pd/C / ethyl acetate; ethanol / 2 h / 20 °C

4.1: 20.6 mg / TBAF / tetrahydrofuran / 1 h / 20 °C

With n-butyllithium; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; hexane; dichloromethane; ethyl acetate;
DOI:10.1021/ol7016388