isovaleryl-L-valyl-4(S)-amino-3(S)-hydroxy-5-phenylpentanoyl-L-alanyl isoamylamide

Base Information

• Chemical Name: isovaleryl-L-valyl-4(S)-amino-3(S)-hydroxy-5-phenylpentanoyl-L-alanyl isoamylamide
• CAS No.: 75846-13-8
• Molecular Formula: C₂₉H₄₈N₄O₅
• Molecular Weight: 532.724
• Mol file: 75846-13-8.mol

Synonyms:isovaleryl-L-valyl-4(S)-amino-3(S)-hydroxy-5-phenylpentanoyl-L-alanyl isoamylamide

Chemical Property of isovaleryl-L-valyl-4(S)-amino-3(S)-hydroxy-5-phenylpentanoyl-L-alanyl isoamylamide

Chemical Property:

Purity/Quality:

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Technology Process of isovaleryl-L-valyl-4(S)-amino-3(S)-hydroxy-5-phenylpentanoyl-L-alanyl isoamylamide

There total 1 articles about isovaleryl-L-valyl-4(S)-amino-3(S)-hydroxy-5-phenylpentanoyl-L-alanyl isoamylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(Iva-L-Val)2O + (3S,4S)-AHPPA-Ala-NHiC5H11*HCl (72155-68-1) → isovaleryl-L-valyl-4(S)-amino-3(S)-hydroxy-5-phenylpentanoyl-L-alanyl isoamylamide (75846-13-8)

Guidance literature:

With triethylamine; In dichloromethane; N,N-dimethyl-formamide; 1.) 4 deg C, 40 h, 2.) RT, 3 h;

DOI:10.1021/jm00175a006

Reference yield:

isovaleryl-L-valyl-4(S)-amino-3(S)-hydroxy-5-phenylpentanoyl-L-alanyl isoamylamide (75846-13-8) → (S)-2-[(3S,4S)-4-((S)-2-Amino-3-methyl-butyrylamino)-3-hydroxy-5-phenyl-pentanoylamino]-propionic acid

Guidance literature:

With hydrogenchloride; In propionic acid; at 130 ℃; for 3h;

DOI:10.1021/jm00175a006

upstream raw materials:

(3S,4S)-AHPPA-Ala-NHⁱC₅H₁₁*HCl