N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-nitrobenzamide

Base Information

Chemical Name:N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-nitrobenzamide
CAS No.:872332-66-6
Molecular Formula:C₂₂H₂₅F₃N₄O₃
Molecular Weight:450.461
Hs Code.:

Synonyms:N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-nitrobenzamide

Suppliers and Price of N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-nitrobenzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-nitrobenzamide

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Technology Process of N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-nitrobenzamide

There total 9 articles about N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 630125-91-6
4-(4-ethylpiperazin-1-ylmethyl)-3-trifluoromethylphenylamine

: 872332-66-6
N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-nitrobenzamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 0.5h;

Reference yield: 87.1%

: 630125-91-6
4-(4-ethylpiperazin-1-ylmethyl)-3-trifluoromethylphenylamine

: 96-98-0
4-methyl-3-nitrobenzoic acid

: 872332-66-6
N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-nitrobenzamide

Guidance literature:: With dmap; N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1021/acsmedchemlett.1c00030