Ethyl N-Boc-piperidine-4-carboxylate

Base Information

• Chemical Name: Ethyl N-Boc-piperidine-4-carboxylate
• CAS No.: 142851-03-4
• Molecular Formula: C13H23NO4
• Molecular Weight: 257.33
• Hs Code.: 29333990
• European Community (EC) Number: 629-436-5
• DSSTox Substance ID: DTXSID20374497
• Nikkaji Number: J1.745.648B
• Wikidata: Q72473065
• ChEMBL ID: CHEMBL3181993
• Mol file: 142851-03-4.mol

Synonyms:142851-03-4;Ethyl N-Boc-piperidine-4-carboxylate;1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate;ethyl n-boc-4-piperidinecarboxylate;1-boc-piperidine-4-carboxylic acid ethyl ester;1,4-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) 4-ethyl ester;1-O-tert-butyl 4-O-ethyl piperidine-1,4-dicarboxylate;MFCD01763998;1-boc-isonipecotic acid ethyl ester;Ethyl 1-tert-Butoxycarbonylpiperidine-4-carboxylate;Ethyl 1-(tert-Butyloxycarbonyl)isonipecotate;1-tert-butyl-4-ethylpiperidine-1,4-dicarboxylate;Piperidine-1,4-dicarboxylic Acid 1-tert-Butyl 4-Ethyl Ester;ethyl n-boc-isonipecotate;Piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester;ethyl 1-boc-piperidine-4-carboxylate;Ethyl 1-Boc-4-piperidinecarboxylate;EthylN-Boc-piperidine-4-carboxylate;Ethyl-N-BOC-piperidine-4-carboxylate;1-Boc-piperidine-4-carboxylicacidethylester;ethyl-N-boc-isonipecotate;SCHEMBL337418;O1-tert-butyl O4-ethyl piperidine-1,4-dicarboxylate;CHEMBL3181993;DTXSID20374497;MYHJCTUTPIKNAT-UHFFFAOYSA-N;1-(tert-butyl) 4-ethyl tetrahydro-1,4(2h)-pyridinedicarboxylate;BCP22255;Ethyl N-Bocpiperidine-4-carboxylate;AB6662;AC-979;BBL018408;STL185663;ethyl N-t-butoxycarbonyl-isonipecotate;AKOS005068018;CS-W020575;ethyl n-(t-butoxycarbonyl)isonipecotate;PB47499;SY002332;AM20080326;Ethyl N-Boc-piperidine-4-carboxylate, 97%;FT-0645163;1-Boc-4-piperidinecarboxylic Acid Ethyl Ester;9N-047;EN300-103823;ethyl N-t-butoxycarbonyl-4-piperidinecarboxylate;1-tert-butoxycarbonylisonipecotic acid ethyl ester;1-tert-butyl 4-ethyl 1,4-piperidinedicarboxylate;ethyl N-t-butyloxycarbonylpiperidine-4-carboxylate;N-tert-butoxycarbonyl isonipecotic acid ethyl ester;1-(tert-butoxycarbonyl)-4-(carboethoxy)-piperidine;1-(tert-butyl) 4-ethyl 1,4-piperidinedicarboxylate;ethyl N-tert-butoxycarbonyl-piperidine-4-carboxylate;Ethyl N-tert-butoxycarbonylpiperidine-4-carboxylate;J-505140;tert-butyl 4-ethoxycarbonylpiperidine-1-carboxylate;W-205473;BRD-K18650194-001-02-9;Ethyl 1-(tert-butoxycarbonyl)-4-piperidinecarboxylate;Ethyl 1-(tert-butoxycarbonyl)piperidine-4-carboxylate;ethyl 1-tert.-butyloxycarbonylpiperidine-4-carboxylate;tert-butyl 4-(ethoxycarbonyl)-1-piperidinecarboxylate;TERT-BUTYL ETHYL PIPERIDINE-1,4-DICARBOXYLATE;F8881-5699;1-(1,1-dimethylethyl) 4-ethyl 1,4-piperidinedicarboxylate;1-tert-butoxycarbonylpipendine-4-carboxylic acid ethyl ester;1-(tert-Butoxycarbonyl)-4-piperidinecarboxylic Acid Ethyl Ester;1-tert-butoxycarbonylpiperidine-4-carboxylic acid ethyl ester;piperidine-1,4-dicarboxylic acid tert-butyl ester ethyl ester;piperidine-1,4-dicarboxylic acid 1-tert-butylester 4-ethyl ester;piperidine-1,4-dicarboxylic acid l-tert-butyl ester 4-ethyl ester;piperidine-1,4-dicarboxylic acid-1-tert butyl ester-4-ethyl ester;piperidine-1,4-dicarboxylic acid-1-tert-butyl ester 4-ethyl ester;piperidine-1,4-dicarboxylic acid-1-tert-butyl ester-4-ethyl ester;4-(ethoxy-carbonyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester

Chemical Property of Ethyl N-Boc-piperidine-4-carboxylate

Chemical Property:

• Appearance/Colour: white crystalline power
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: n20/D 1.458
• Boiling Point: 323.9 °C at 760 mmHg
• PKA: -2.23±0.40(Predicted)
• Flash Point: 149.7 °C
• PSA: 55.84000
• Density: 1.077 g/cm³
• LogP: 2.13450
• Storage Temp.: 0-10°C
• Solubility.: Chloroform, Ethyl Acetate
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 257.16270821
• Heavy Atom Count: 18
• Complexity: 301

Purity/Quality:

98% Min ^*data from raw suppliers

Ethyl N-Boc-piperidine-4-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1CCN(CC1)C(=O)OC(C)(C)C
• Uses: Ethyl N-Boc-piperidine-4-carboxylate is used as a reagent to synthesize 3-amino-1-(5-indanyloxy)-2-propanol derivatives as sodium channel blockers to treat stroke patients. Ethyl N-Boc-piperidine-4-carboxylate is also used as a reagent to prepare inhibitors of tumour necrosis factor alpha-converting enzyme. Substrate used in a palladium-catalyzed α-arylation of esters with heterocyclic bromides and chlorides leading to, for example, 4-pyridylpiperidinyl esters.