2-(1,1-Bis-phenylsulfanyl-ethyl)-5-methoxy-benzo[1,3]oxathiole 3,3-dioxide

Base Information

• Chemical Name: 2-(1,1-Bis-phenylsulfanyl-ethyl)-5-methoxy-benzo[1,3]oxathiole 3,3-dioxide
• CAS No.: 181510-05-4
• Molecular Formula: C₂₂H₂₀O₄S₃
• Molecular Weight: 444.596
• Mol file: 181510-05-4.mol

Synonyms:2-(1,1-Bis-phenylsulfanyl-ethyl)-5-methoxy-benzo[1,3]oxathiole 3,3-dioxide

Chemical Property of 2-(1,1-Bis-phenylsulfanyl-ethyl)-5-methoxy-benzo[1,3]oxathiole 3,3-dioxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(1,1-Bis-phenylsulfanyl-ethyl)-5-methoxy-benzo[1,3]oxathiole 3,3-dioxide

There total 1 articles about 2-(1,1-Bis-phenylsulfanyl-ethyl)-5-methoxy-benzo[1,3]oxathiole 3,3-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

thiophenol (108-98-5) + 2-acetyl-5-methoxy-1,3-benzoxathiole 3,3-dioxide (122324-35-0) → 5-Methoxy-2-[1-phenylsulfanyl-eth-(E)-ylidene]-benzo[1,3]oxathiole 3,3-dioxide (850582-33-1) + 2-(1,1-Bis-phenylsulfanyl-ethyl)-5-methoxy-benzo[1,3]oxathiole 3,3-dioxide (181510-05-4)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 40h; Heating;

DOI:10.1002/ardp.19963290706

Reference yield: 81.0%

2-(1,1-Bis-phenylsulfanyl-ethyl)-5-methoxy-benzo[1,3]oxathiole 3,3-dioxide (181510-05-4) → 5-Methoxy-2-[1-phenylsulfanyl-eth-(E)-ylidene]-benzo[1,3]oxathiole 3,3-dioxide (850582-33-1)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 1h; Heating;

DOI:10.1002/ardp.19963290706

Reference yield:

2-(1,1-Bis-phenylsulfanyl-ethyl)-5-methoxy-benzo[1,3]oxathiole 3,3-dioxide (181510-05-4) → 2-[1-Benzenesulfinyl-eth-(E)-ylidene]-5-methoxy-benzo[1,3]oxathiole 3,3-dioxide

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / pTSA*H₂O / toluene / 1 h / Heating

2: 82 percent / mCPBA / CH₂Cl₂ / 2 h / -20 °C

With toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; toluene;

DOI:10.1002/ardp.19963290706

upstream raw materials:

thiophenol

2-acetyl-5-methoxy-1,3-benzoxathiole 3,3-dioxide

Downstream raw materials:

5-Methoxy-2-[1-phenylsulfanyl-eth-(E)-ylidene]-benzo[1,3]oxathiole 3,3-dioxide