2--1,2-dihydroisoquinaldonitrile

Base Information

Chemical Name:2--1,2-dihydroisoquinaldonitrile
CAS No.:77287-54-8
Molecular Formula:C₁₈H₁₃BrN₂O
Molecular Weight:353.218
Hs Code.:

2-<o-(Bromomethyl)benzoyl>-1,2-dihydroisoquinaldonitrile

Synonyms:2--1,2-dihydroisoquinaldonitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2--1,2-dihydroisoquinaldonitrile

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Technology Process of 2--1,2-dihydroisoquinaldonitrile

There total 1 articles about 2--1,2-dihydroisoquinaldonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 119-65-3
isoquinoline

: 7115-90-4
α-Bromo-o-toluyl Chloride

: 151-50-8
potassium cyanide

: 77287-54-8
2--1,2-dihydroisoquinaldonitrile

Guidance literature:: With N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; water; at 0 ℃; for 0.166667h;
DOI:10.1021/jo00325a010

Reference yield: 50.0%

: 77287-54-8
2--1,2-dihydroisoquinaldonitrile

: 77287-53-7
2-(o-Formylbenzoyl)-1,2-dihydroisoquinaldonitrile

Guidance literature:: With silver tetrafluoroborate; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; Ambient temperature; 1.) 39 h, 2.) 15 min;
DOI:10.1021/jo00325a010