methyl 2,2-dimethoxy-3-(triethylsilyl)oxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate

Base Information

Chemical Name:methyl 2,2-dimethoxy-3-(triethylsilyl)oxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate
CAS No.:221684-57-7
Molecular Formula:C₂₂H₃₀O₅Si
Molecular Weight:402.563
Hs Code.:

Synonyms:methyl 2,2-dimethoxy-3-(triethylsilyl)oxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate

Suppliers and Price of methyl 2,2-dimethoxy-3-(triethylsilyl)oxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2,2-dimethoxy-3-(triethylsilyl)oxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2,2-dimethoxy-3-(triethylsilyl)oxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate

There total 9 articles about methyl 2,2-dimethoxy-3-(triethylsilyl)oxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 79271-56-0
triethylsilyl trifluoromethyl sulfonate

: 221684-56-6
methyl 2,2-dimethoxy-3-hydroxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate

: 221684-57-7
methyl 2,2-dimethoxy-3-(triethylsilyl)oxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; at 0 ℃; for 0.75h;
DOI:10.1016/S0040-4020(98)01204-6

Reference yield:

: 303-38-8
2,3-Dihydroxybenzoic acid

: 221684-57-7
methyl 2,2-dimethoxy-3-(triethylsilyl)oxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate

Guidance literature:: Multi-step reaction with 8 steps

1: 94 percent / thionyl chloride / 16 h / 50 °C

2: 86 percent / K₂CO₃ / CH₂Cl₂ / 1.5 h / 0 °C

3: 84 percent / K₂CO₃ / dimethylformamide / 1.5 h / 35 °C

4: 89 percent / K₂CO₃ / methanol / 3 h / Ambient temperature

5: 91 percent / iodobenzene diacetate / 0.5 h / 0 °C

6: 90 percent / tetrahydrofuran / 0.75 h / -78 °C

7: 98 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C

8: 95 percent / 2,6-lutidine / CH₂Cl₂ / 0.75 h / 0 °C

With 2,6-dimethylpyridine; thionyl chloride; [bis(acetoxy)iodo]benzene; tetrabutyl ammonium fluoride; potassium carbonate; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(98)01204-6

Reference yield:

: 2169-25-7
methyl 3′-hydroxy-2′-methoxybenzoate

: 221684-57-7
methyl 2,2-dimethoxy-3-(triethylsilyl)oxy-3-<(Z)-hexa-1,5-diyne-3-ene>cyclohex-4,6-diene-1-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 91 percent / iodobenzene diacetate / 0.5 h / 0 °C

2: 90 percent / tetrahydrofuran / 0.75 h / -78 °C

3: 98 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C

4: 95 percent / 2,6-lutidine / CH₂Cl₂ / 0.75 h / 0 °C

With 2,6-dimethylpyridine; [bis(acetoxy)iodo]benzene; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4020(98)01204-6