C₁₆H₁₈F₃NO₃

Base Information

Chemical Name:C₁₆H₁₈F₃NO₃
CAS No.:1234791-00-4
Molecular Formula:C₁₆H₁₈F₃NO₃
Molecular Weight:329.319
Hs Code.:

C<sub>16</sub>H<sub>18</sub>F<sub>3</sub>NO<sub>3</sub>

Synonyms:C₁₆H₁₈F₃NO₃

Suppliers and Price of C₁₆H₁₈F₃NO₃

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₁₆H₁₈F₃NO₃

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₁₆H₁₈F₃NO₃

There total 3 articles about C₁₆H₁₈F₃NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1234790-99-8
C₁₄H₁₂F₃NO₃

: 925-90-6
ethylmagnesium bromide

: 1234791-00-4
C₁₆H₁₈F₃NO₃

Guidance literature:: C₁₄H₁₂F₃NO₃; ethylmagnesium bromide; In tetrahydrofuran; at 20 ℃; Cooling with ice;

With ammonium chloride; In tetrahydrofuran; water;

Reference yield:

: 1186482-11-0
1-bromo-4-propoxy-2-(trifluoromethyl)benzene

: 1234791-00-4
C₁₆H₁₈F₃NO₃

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-butyllithium / hexanes; diethyl ether / Cooling with acetone-dry ice; Inert atmosphere

1.2: 20 °C / Cooling with acetone-dry ice

1.3: 0.25 h

2.1: hydroxylamine / ethanol; water / 2 h / 20 °C

3.1: pyridine; N-chloro-succinimide / tetrahydrofuran / 0.75 h / 60 °C / Inert atmosphere

3.2: 60 °C

4.1: Dess-Martin periodane / dichloromethane / 1 h / 20 °C

5.1: tetrahydrofuran / 20 °C / Cooling with ice

With pyridine; N-chloro-succinimide; n-butyllithium; hydroxylamine; Dess-Martin periodane; In tetrahydrofuran; hexanes; diethyl ether; ethanol; dichloromethane; water;

Reference yield:

: 40161-55-5
1-bromo-4-fluoro-2-(trifluoromethyl)benzene

: 1234791-00-4
C₁₆H₁₈F₃NO₃

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydride / mineral oil / 20 - 145 °C / Microwave irradiation; Sealed tube

2.1: n-butyllithium / hexanes; diethyl ether / Cooling with acetone-dry ice; Inert atmosphere

2.2: 20 °C / Cooling with acetone-dry ice

2.3: 0.25 h

3.1: hydroxylamine / ethanol; water / 2 h / 20 °C

4.1: pyridine; N-chloro-succinimide / tetrahydrofuran / 0.75 h / 60 °C / Inert atmosphere

4.2: 60 °C

5.1: Dess-Martin periodane / dichloromethane / 1 h / 20 °C

6.1: tetrahydrofuran / 20 °C / Cooling with ice

With pyridine; N-chloro-succinimide; n-butyllithium; hydroxylamine; sodium hydride; Dess-Martin periodane; In tetrahydrofuran; hexanes; diethyl ether; ethanol; dichloromethane; water; mineral oil;