4-Methoxy-3-[(5-methoxy-2-pyridinyl)methyl]phenol

Base Information

Chemical Name:4-Methoxy-3-[(5-methoxy-2-pyridinyl)methyl]phenol
CAS No.:105170-29-4
Molecular Formula:C₁₄H₁₅NO₃
Molecular Weight:245.278
Hs Code.:
DSSTox Substance ID:DTXSID101233281

Synonyms:4-Methoxy-3-[(5-methoxy-2-pyridinyl)methyl]phenol;SCHEMBL7283400;DTXSID101233281;105170-29-4

Suppliers and Price of 4-Methoxy-3-[(5-methoxy-2-pyridinyl)methyl]phenol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Methoxy-3-[(5-methoxy-2-pyridinyl)methyl]phenol

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:245.10519334
Heavy Atom Count:18
Complexity:249

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CN=C(C=C1)CC2=C(C=CC(=C2)O)OC

Technology Process of 4-Methoxy-3-[(5-methoxy-2-pyridinyl)methyl]phenol

There total 4 articles about 4-Methoxy-3-[(5-methoxy-2-pyridinyl)methyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1-(3-benzyloxy-6-methoxyphenyl)-1-(5-methoxy-pyridin-2-yl)-methyl acetate

: 105170-29-4
4-methoxy-3-<(5-methoxypyridin-2-yl)methyl>phenol

Guidance literature:: With hydrogenchloride; palladium on charcoal; In acetic acid;

Reference yield: 64.0%

: Acetic acid (5-benzyloxy-2-methoxy-phenyl)-(5-methoxy-pyridin-3-yl)-methyl ester

: 105170-29-4
4-methoxy-3-<(5-methoxypyridin-2-yl)methyl>phenol

Guidance literature:: With hydrogen; palladium on activated charcoal; In water; acetic acid; for 1.5h; under 2585.7 Torr;
DOI:10.1039/P19880003085

Reference yield:

: 52329-06-3
5-(benzyloxy)-2-methoxybenzaldehyde

: 105170-29-4
4-methoxy-3-<(5-methoxypyridin-2-yl)methyl>phenol

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / butyl-lithium / hexane; tetrahydrofuran / -90 deg C, -80 deg C, 10 min, RT

2: pyridine / 100 °C

3: 64 percent / H₂ / 10percent Pd/C / acetic acid; H₂O / 1.5 h / 2585.7 Torr

With pyridine; n-butyllithium; hydrogen; palladium on activated charcoal; In tetrahydrofuran; hexane; water; acetic acid;
DOI:10.1039/P19880003085