Technology Process of 1,3-dimethyl-4-(3-phenylpropyl)-1,2,5,6-tetrahydropyridine
There total 5 articles about 1,3-dimethyl-4-(3-phenylpropyl)-1,2,5,6-tetrahydropyridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide; sodium tetrahydroborate;
In
ethanol;
1.) ice-cooling, 2 h, 2.) room temp., 24 h;
DOI:10.1002/ardp.19873200502
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) Mg / 1.) ether, 40 deg C, 1 h, 2.) room temp., 3 h then 40 deg C, 2 h
2: 83 percent / 80percent aq. NH2NH2*H2O, KOH / various solvent(s) / 120 deg C, 2 h then 160 deg C, 2 h, 195 deg C, 2 h
3: 97 percent / acetone / 0.5 h / Heating
4: 81 percent / 2 N NaOH, NaBH4 / aq. ethanol / 1.) ice-cooling, 2 h, 2.) room temp., 24 h
With
potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; hydrazine hydrate; magnesium;
In
ethanol; acetone;
DOI:10.1002/ardp.19873200502
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) Mg / 1.) ether, 40 deg C, 1 h, 2.) room temp., 3 h then 40 deg C, 2 h
2: 83 percent / 80percent aq. NH2NH2*H2O, KOH / various solvent(s) / 120 deg C, 2 h then 160 deg C, 2 h, 195 deg C, 2 h
3: 97 percent / acetone / 0.5 h / Heating
4: 81 percent / 2 N NaOH, NaBH4 / aq. ethanol / 1.) ice-cooling, 2 h, 2.) room temp., 24 h
With
potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; hydrazine hydrate; magnesium;
In
ethanol; acetone;
DOI:10.1002/ardp.19873200502
