(S)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate

Base Information

Chemical Name:(S)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate
CAS No.:107202-39-1
Molecular Formula:C13H25NO3
Molecular Weight:243.346
Hs Code.:2924299090
European Community (EC) Number:624-491-1
DSSTox Substance ID:DTXSID10584528
Wikidata:Q72449043
Mol file:107202-39-1.mol

Synonyms:107202-39-1;N-Boc-L-cyclohexylglycinol;(S)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate;MFCD04112591;TERT-BUTYL N-[(1S)-1-CYCLOHEXYL-2-HYDROXYETHYL]CARBAMATE;(S)-tert-Butyl(1-cyclohexyl-2-hydroxyethyl)carbamate;SCHEMBL12733104;DTXSID10584528;N-Boc-L-cyclohexylglycinol, 98%;AKOS015914375;AKOS016015598;CS-W010266;AS-10096;(2S)-2-(Boc-amino)-2-(cyclohexyl)ethanol;N-BOC-L-2-AMINO-2-CYCLOHEXYL-ETHANOL;F14506;EN300-6262693;A895675;J-001729;tert-Butyl [(1S)-1-cyclohexyl-2-hydroxyethyl]carbamate;Carbamic acid,N-[(1S)-1-cyclohexyl-2-hydroxyethyl]-,1,1-dimethylethyl ester

Suppliers and Price of (S)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
N-Boc-L-cyclohexylglycinol
5 g
$ 496.00

SynQuest Laboratories
N-Boc-L-cyclohexylglycinol
1 g
$ 168.00

Sigma-Aldrich
N-Boc-L-cyclohexylglycinol 98%
1g
$ 83.10

Sigma-Aldrich
N-Boc-L-cyclohexylglycinol 98%
5g
$ 320.00

Crysdot
(S)-tert-Butyl(1-cyclohexyl-2-hydroxyethyl)carbamate 95+%
25g
$ 600.00

Crysdot
(S)-tert-Butyl(1-cyclohexyl-2-hydroxyethyl)carbamate 95+%
10g
$ 294.00

Chemenu
(S)-tert-Butyl(1-cyclohexyl-2-hydroxyethyl)carbamate 95%
25g
$ 655.00

Chemenu
(S)-tert-Butyl(1-cyclohexyl-2-hydroxyethyl)carbamate 95%
5g
$ 204.00

Chemenu
(S)-tert-Butyl(1-cyclohexyl-2-hydroxyethyl)carbamate 95%
10g
$ 327.00

Apolloscientific
N-t-BOC-L-Cyclohexylglycinol
1g
$ 153.00

Total 45 raw suppliers

Chemical Property of (S)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate

Chemical Property:

Vapor Pressure:5.05E-07mmHg at 25°C
Melting Point:83-87 ºC
Refractive Index:1.482
Boiling Point:371.2 ºC at 760 mmHg
PKA:12.07±0.46(Predicted)
Flash Point:178.3 ºC
PSA：58.56000
Density:1.037 g/cm³
LogP:2.84320
Storage Temp.:Store at 0-5°C
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:243.18344366
Heavy Atom Count:17
Complexity:242

Purity/Quality:

98%, ^*data from raw suppliers

N-Boc-L-cyclohexylglycinol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CO)C1CCCCC1
Isomeric SMILES:CC(C)(C)OC(=O)N[C@H](CO)C1CCCCC1

Technology Process of (S)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate

There total 11 articles about (S)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.17%

: 109183-71-3
N-(tert-butoxycarbonyl)-L-cyclohexylglycine

: 543-27-1
isobutyl chloroformate

: 107202-39-1
(S)-1-(cyclohexyl-2-hydroxyethyl)crabamic acid tert-butyl ester

Guidance literature:: N-(tert-butoxycarbonyl)-L-cyclohexylglycine; isobutyl chloroformate; With 4-methyl-morpholine; In tetrahydrofuran; at -10 - 20 ℃; for 0.5h; Inert atmosphere;

With sodium tetrahydroborate; water; In tetrahydrofuran; at -10 ℃; for 1h; Inert atmosphere;

Reference yield: 66.0%

: C₁₇H₂₉NO₆

: 107202-39-1
(S)-1-(cyclohexyl-2-hydroxyethyl)crabamic acid tert-butyl ester

Guidance literature:: With sodium tetrahydroborate; In water; at 0 ℃;
DOI:10.1016/j.bmcl.2003.09.088

Reference yield:

: 109183-71-3
N-(tert-butoxycarbonyl)-L-cyclohexylglycine

: 107202-39-1
(S)-1-(cyclohexyl-2-hydroxyethyl)crabamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: NEt₃ / tetrahydrofuran / -10 °C

2: 66 percent / NaBH₄ / H₂O / 0 °C

With sodium tetrahydroborate; triethylamine; In tetrahydrofuran; water;
DOI:10.1016/j.bmcl.2003.09.088