4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-5-phenylpentanoic acid

Base Information

Chemical Name:4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-5-phenylpentanoic acid
CAS No.:72155-48-7
Molecular Formula:C16H23 N O5
Molecular Weight:309.362
Hs Code.:29225090
DSSTox Substance ID:DTXSID10405729
Mol file:72155-48-7.mol

Synonyms:4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-5-phenylpentanoic acid;4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-oxidanyl-5-phenyl-pentanoic acid;DTXSID10405729;EN300-718087;2,4,5-Trideoxy-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-phenylpentonic acid;4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxy-5-phenylpentanoic acid;1822423-82-4

Suppliers and Price of 4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-5-phenylpentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Boc-(3S,4S)-4-amino-3-hydroxy-5-phenylpentanoicAcid
25mg
$ 85.00

Iris Biotech GmbH
Boc-(3S,4S)-AHPPA-OH
250 mg
$ 337.50

Crysdot
(3S,4S)-4-((tert-Butoxycarbonyl)amino)-3-hydroxy-5-phenylpentanoicacid 97%
1g
$ 489.00

Biosynth Carbosynth
Boc-(3S,4S)-4-amino-3-hydroxy-5-phenylpentanoic acid
250 mg
$ 400.00

Biosynth Carbosynth
Boc-(3S,4S)-4-amino-3-hydroxy-5-phenylpentanoic acid
25 mg
$ 75.00

Biosynth Carbosynth
Boc-(3S,4S)-4-amino-3-hydroxy-5-phenylpentanoic acid
100 mg
$ 200.00

Biosynth Carbosynth
Boc-(3S,4S)-4-amino-3-hydroxy-5-phenylpentanoic acid
50 mg
$ 125.00

Biosynth Carbosynth
Boc-(3S,4S)-4-amino-3-hydroxy-5-phenylpentanoic acid
500 mg
$ 750.00

American Custom Chemicals Corporation
BOC-4-AMINO-3-HYDROXY-5-PHENYL-PENTANOIC ACID 98.00%
1G
$ 1848.00

AK Scientific
Boc-Ahppa-OH
100mg
$ 95.00

Total 12 raw suppliers

Chemical Property of 4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-5-phenylpentanoic acid

Chemical Property:

Melting Point:88 °C
Boiling Point:528.1±50.0 °C(Predicted)
PKA:4.21±0.10(Predicted)
PSA：95.86000
Density:1.191±0.06 g/cm3(Predicted)
LogP:2.34890
Storage Temp.:2-8°C
XLogP3:4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:431.17327290
Heavy Atom Count:32
Complexity:612

Purity/Quality:

97% ^*data from raw suppliers

Boc-(3S,4S)-4-amino-3-hydroxy-5-phenylpentanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(CC(=O)O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Technology Process of 4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-5-phenylpentanoic acid

There total 39 articles about 4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-5-phenylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 109579-10-4,109579-13-7,144186-19-6
(4S,5R)-N-(((tert)-butyloxy)carbonyl)-5-benzyl-4-hydroxy-2-pyrrolidinone

: 72155-48-7
(3S,4S)-4-tert-butoxycarbonylamino-3-hydroxy-5-phenylpentanoic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane;
DOI:10.1016/S0040-4039(98)02409-5

Reference yield: 81.0%

: 101669-80-1
methyl (3S,4S)-N-tert-butoxycarbonyl-4-amino-3-hydroxy-5-phenylpentanoate

: 72155-48-7
(3S,4S)-4-tert-butoxycarbonylamino-3-hydroxy-5-phenylpentanoic acid

Guidance literature:: methyl (3S,4S)-N-tert-butoxycarbonyl-4-amino-3-hydroxy-5-phenylpentanoate; With water; sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; water; Cooling;
DOI:10.1016/j.tetasy.2011.09.021