2-((tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid

Base Information

Chemical Name:2-((tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid
CAS No.:301196-85-0
Molecular Formula:C₁₄H₁₆F₃NO₅
Molecular Weight:335.28
Hs Code.:

Synonyms:2-((tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid

Suppliers and Price of 2-((tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Activate Scientific
N-Boc-2-(4-trifluoromethoxyphenyl)glycine 95+%
1 g
$ 333.00

Activate Scientific
N-Boc-2-(4-trifluoromethoxyphenyl)glycine 95+%
5 g
$ 1159.00

Acrotein
N-Boc-2-(4-trifluoromethoxyphenyl)glycine 97%
5g
$ 843.33

Total 4 raw suppliers

Chemical Property of 2-((tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

N-Boc-2-(4-trifluoromethoxyphenyl)glycine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-((tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid

There total 6 articles about 2-((tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl (2-amino-2-oxo-1-(4-(trifluoromethoxy)phenyl)ethyl)carbamate

: 301196-85-0
2-((tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid

Guidance literature:: With water; sodium hydroxide; In methanol; for 20h; Temperature; Reflux;

Reference yield:

: 659-28-9
p-trifluoromethoxybenzaldehyde

: 301196-85-0
2-((tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: ammonia; titanium(IV) isopropylate / methanol / 0.25 h / 0 °C

1.2: 20 h / 0 - 35 °C

2.1: water; potassium hydroxide / 72 h / 90 °C

3.1: sodium hydroxide / water; tetrahydrofuran / 10 - 35 °C

With titanium(IV) isopropylate; ammonia; water; potassium hydroxide; sodium hydroxide; In tetrahydrofuran; methanol; water;

Reference yield:

: 954582-33-3
amino(4-(trifluoromethoxy)phenyl)acetonitrile

: 301196-85-0
2-((tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: water; potassium hydroxide / 72 h / 90 °C

2: sodium hydroxide / water; tetrahydrofuran / 10 - 35 °C

With water; potassium hydroxide; sodium hydroxide; In tetrahydrofuran; water;