C₁₉H₃₆O₂Si

Base Information

• Chemical Name: C₁₉H₃₆O₂Si
• CAS No.: 1354005-97-2
• Molecular Formula: C₁₉H₃₆O₂Si
• Molecular Weight: 324.579
• Mol file: 1354005-97-2.mol

Synonyms:C₁₉H₃₆O₂Si

Chemical Property of C₁₉H₃₆O₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₃₆O₂Si

There total 11 articles about C₁₉H₃₆O₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C27H44O3Si (1354005-85-8) → C19H36O2Si (1354005-97-2)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at 0 ℃; for 1.5h; pH=7; aq. phosphate buffer;

DOI:10.1016/j.tetlet.2011.10.151

Reference yield:

C21H30O3 → C19H36O2Si (1354005-97-2)

Guidance literature:

Multi-step reaction with 6 steps

1.1: Dess-Martin periodane / dichloromethane / 1 h / 0 °C

2.1: borane-THF; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole / tetrahydrofuran / 6 h / -40 °C

3.1: sodium bis(2-methoxyethoxy)aluminium dihydride / 4 h / 40 °C

3.2: 12 h / -78 - 0 °C

4.1: 2,6-dimethylpyridine / dichloromethane / 0.17 h / 20 °C

5.1: palladium diacetate; triethylamine; tris-(o-tolyl)phosphine / water; acetonitrile / 1.5 h / 80 °C

6.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 1.5 h / 0 °C / pH 7 / aq. phosphate buffer

With 2,6-dimethylpyridine; borane-THF; palladium diacetate; Dess-Martin periodane; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; tris-(o-tolyl)phosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole; In tetrahydrofuran; dichloromethane; water; acetonitrile; 5.1: Heck reaction;

DOI:10.1016/j.tetlet.2011.10.151

Reference yield:

C16H24O3 (1354005-88-1) → C19H36O2Si (1354005-97-2)

Guidance literature:

Multi-step reaction with 9 steps

1.1: mercury(II) diacetate / 36 h / Reflux

2.1: methylaluminium bis(4-bromo-2,6-di-tert.-butylphenoxide) / dichloromethane / 0.25 h / -78 °C

3.1: n-butyllithium / tetrahydrofuran

3.2: 2 h / -78 °C

4.1: Dess-Martin periodane / dichloromethane / 1 h / 0 °C

5.1: borane-THF; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole / tetrahydrofuran / 6 h / -40 °C

6.1: sodium bis(2-methoxyethoxy)aluminium dihydride / 4 h / 40 °C

6.2: 12 h / -78 - 0 °C

7.1: 2,6-dimethylpyridine / dichloromethane / 0.17 h / 20 °C

8.1: palladium diacetate; triethylamine; tris-(o-tolyl)phosphine / water; acetonitrile / 1.5 h / 80 °C

9.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 1.5 h / 0 °C / pH 7 / aq. phosphate buffer

With 2,6-dimethylpyridine; n-butyllithium; borane-THF; mercury(II) diacetate; palladium diacetate; Dess-Martin periodane; methylaluminium bis(4-bromo-2,6-di-tert.-butylphenoxide); triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; tris-(o-tolyl)phosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole; In tetrahydrofuran; dichloromethane; water; acetonitrile; 2.1: Claisen rearrangement / 8.1: Heck reaction;

DOI:10.1016/j.tetlet.2011.10.151

upstream raw materials:

C₂₇H₄₄O₃Si

C₁₆H₂₄O₃

C₁₈H₂₆O₃

t-butyldimethylsiyl triflate

Downstream raw materials:

C₁₉H₃₄O₂Si

(E)-4-((1R,4R)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl)-but-3-en-2-one

(3R,6R,7E,9R)-3,9-dihydroxy-4,7-megastigmadiene