N-p-methoxybenzyl-4-(2-hydroxy-2-phenylethyl)-4-piperidinol hydrochloride

Base Information

Chemical Name:N-p-methoxybenzyl-4-(2-hydroxy-2-phenylethyl)-4-piperidinol hydrochloride
CAS No.:1064708-55-9
Molecular Formula:C₂₁H₂₇NO₃*ClH
Molecular Weight:377.911
Hs Code.:

Synonyms:N-p-methoxybenzyl-4-(2-hydroxy-2-phenylethyl)-4-piperidinol hydrochloride

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Chemical Property of N-p-methoxybenzyl-4-(2-hydroxy-2-phenylethyl)-4-piperidinol hydrochloride

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Technology Process of N-p-methoxybenzyl-4-(2-hydroxy-2-phenylethyl)-4-piperidinol hydrochloride

There total 5 articles about N-p-methoxybenzyl-4-(2-hydroxy-2-phenylethyl)-4-piperidinol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.4%

: 1064708-30-0
N-p-methoxybenzyl-4-benzoylmethyl-4-piperidinol hydrochloride

: 1064708-55-9
N-p-methoxybenzyl-4-(2-hydroxy-2-phenylethyl)-4-piperidinol hydrochloride

Guidance literature:: N-p-methoxybenzyl-4-benzoylmethyl-4-piperidinol hydrochloride; With sodium tetrahydroborate; In ethanol; at 20 ℃;

With hydrogenchloride; In ethanol; pH=2;

Reference yield:

: 1064709-28-9
N-p-methoxybenzyl-4-(2-hydroxy-2-phenylethyl)-4-piperidinol

: 1064708-55-9
N-p-methoxybenzyl-4-(2-hydroxy-2-phenylethyl)-4-piperidinol hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; pH=2;

Reference yield:

: 1064708-73-1
4-benzoylmethyl-4-piperidinol

: 1064708-55-9
N-p-methoxybenzyl-4-(2-hydroxy-2-phenylethyl)-4-piperidinol hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 8 h / Reflux

2: sodium tetrahydroborate / ethanol / 20 °C

3: hydrogenchloride / ethanol / pH 2

With hydrogenchloride; sodium tetrahydroborate; potassium carbonate; In ethanol; acetone;