methyl 6-O-(3-O-acetyl-6-O-benzyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonyl-amino)-β-D-glucopyranosyl)-2,3,4-tri-O-benzyl-α-D-glucopyranoside

Base Information

• Chemical Name: methyl 6-O-(3-O-acetyl-6-O-benzyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonyl-amino)-β-D-glucopyranosyl)-2,3,4-tri-O-benzyl-α-D-glucopyranoside
• CAS No.: 1225199-09-6
• Molecular Formula: C₄₆H₅₂Cl₃NO₁₃
• Molecular Weight: 933.277
• Mol file: 1225199-09-6.mol

Synonyms:methyl 6-O-(3-O-acetyl-6-O-benzyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonyl-amino)-β-D-glucopyranosyl)-2,3,4-tri-O-benzyl-α-D-glucopyranoside

Chemical Property of methyl 6-O-(3-O-acetyl-6-O-benzyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonyl-amino)-β-D-glucopyranosyl)-2,3,4-tri-O-benzyl-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 6-O-(3-O-acetyl-6-O-benzyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonyl-amino)-β-D-glucopyranosyl)-2,3,4-tri-O-benzyl-α-D-glucopyranoside

There total 1 articles about methyl 6-O-(3-O-acetyl-6-O-benzyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonyl-amino)-β-D-glucopyranosyl)-2,3,4-tri-O-benzyl-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside (53008-65-4,641635-63-4) + phenyl 3-O-acetyl-2-deoxy-6-O-benzyl-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranoside (1225199-04-1) → methyl 6-O-(3-O-acetyl-6-O-benzyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonyl-amino)-β-D-glucopyranosyl)-2,3,4-tri-O-benzyl-α-D-glucopyranoside (1225199-09-6)

Guidance literature:

With N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; 1-(n-butyl)-3-methylimidazolium triflate; In dichloromethane; at 20 ℃; for 6h; Molecular sieve;

DOI:10.1039/b926177j

Reference yield:

phenyl 2,3,4,5-tetra-O-benzyl-1-thio-β-D-glucopyranoside (38184-10-0) + methyl 6-O-(3-O-acetyl-6-O-benzyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonyl-amino)-β-D-glucopyranosyl)-2,3,4-tri-O-benzyl-α-D-glucopyranoside (1225199-09-6) → methyl 2,3-di-O-benzyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-6-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-α-D-glucopyranoside (1225199-10-9) + methyl 2,3-di-O-benzyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-6-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranoside

Guidance literature:

phenyl 2,3,4,5-tetra-O-benzyl-1-thio-β-D-glucopyranoside; With N-iodo-succinimide; 1-(n-butyl)-3-methylimidazolium triflate; In dichloromethane; at 20 ℃; for 3h; Molecular sieve;

methyl 6-O-(3-O-acetyl-6-O-benzyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonyl-amino)-β-D-glucopyranosyl)-2,3,4-tri-O-benzyl-α-D-glucopyranoside; With N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1039/b926177j

upstream raw materials:

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside

phenyl 3-O-acetyl-2-deoxy-6-O-benzyl-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranoside

Downstream raw materials:

methyl 2,3-di-O-benzyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-6-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-α-D-glucopyranoside