Technology Process of 9,10-dihydro-2,7-diphenyl-9,9-di-n-propylacridine
There total 5 articles about 9,10-dihydro-2,7-diphenyl-9,9-di-n-propylacridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran;
for 3h;
Heating;
DOI:10.1039/b610365k
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 31.7 percent / sulfuric acid / 1 h / 20 °C
2: 40.7 percent / tetra-n-butylammonium tribromide / CHCl3 / 1 h / 20 °C
3: 23.4 percent / aq. K2CO3 / Pd(PPh3)4 / tetrahydrofuran / 3 h / Heating
With
sulfuric acid; tetra-N-butylammonium tribromide; potassium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; chloroform;
3: Suzuki-Miyaura coupling;
DOI:10.1039/b610365k
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sulfuric acid
2.1: Mg / diethyl ether
2.2: 65.5 percent / diethyl ether / 72 h / 20 °C
3.1: 31.7 percent / sulfuric acid / 1 h / 20 °C
4.1: 40.7 percent / tetra-n-butylammonium tribromide / CHCl3 / 1 h / 20 °C
5.1: 23.4 percent / aq. K2CO3 / Pd(PPh3)4 / tetrahydrofuran / 3 h / Heating
With
sulfuric acid; tetra-N-butylammonium tribromide; potassium carbonate; magnesium;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; diethyl ether; chloroform;
5.1: Suzuki-Miyaura coupling;
DOI:10.1039/b610365k
