triethylammonium 5'-O-(dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosine 3'-H-phosphonate

Base Information

Chemical Name:triethylammonium 5'-O-(dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosine 3'-H-phosphonate
CAS No.:118352-76-4
Molecular Formula:C₆H₁₅N*C₃₅H₃₈N₅O₉P
Molecular Weight:804.88
Hs Code.:

Synonyms:triethylammonium 5'-O-(dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosine 3'-H-phosphonate

Suppliers and Price of triethylammonium 5'-O-(dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosine 3'-H-phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of triethylammonium 5'-O-(dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosine 3'-H-phosphonate

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

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Technology Process of triethylammonium 5'-O-(dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosine 3'-H-phosphonate

There total 4 articles about triethylammonium 5'-O-(dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosine 3'-H-phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.8%

: 68892-41-1
5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine

: 121-44-8
triethylamine

: 118352-76-4
triethylammonium 5'-O-(dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosine 3'-H-phosphonate

Guidance literature:: With bis(trichloromethyl) carbonate; phosphonic acid; In acetonitrile; at 0 ℃; for 4h;
DOI:10.1016/0040-4039(95)01383-S

Reference yield:

: C₄₂H₄₄N₅O₉P

: 118352-76-4
triethylammonium 5'-O-(dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosine 3'-H-phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: H₂O, pyridine / 1 h / Ambient temperature

2: H₂O; CH₂Cl₂ / pH 7.0

With pyridine; water; In dichloromethane; water;
DOI:10.1016/0040-4039(96)01993-4

Reference yield:

: 68892-41-1
5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine

: 118352-76-4
triethylammonium 5'-O-(dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosine 3'-H-phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine

2: CH₂Cl₂

With pyridine; In dichloromethane;
DOI:10.1016/S0040-4039(00)76906-1