tert-butyl((3,5-dimethoxycyclohexa-2,5-dien-1-yl)methoxy)diphenylsilane

Base Information

• Chemical Name: tert-butyl((3,5-dimethoxycyclohexa-2,5-dien-1-yl)methoxy)diphenylsilane
• CAS No.: 130472-03-6
• Molecular Formula: C₂₅H₃₂O₃Si
• Molecular Weight: 408.613
• Mol file: 130472-03-6.mol

Synonyms:tert-butyl((3,5-dimethoxycyclohexa-2,5-dien-1-yl)methoxy)diphenylsilane

Chemical Property of tert-butyl((3,5-dimethoxycyclohexa-2,5-dien-1-yl)methoxy)diphenylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl((3,5-dimethoxycyclohexa-2,5-dien-1-yl)methoxy)diphenylsilane

There total 2 articles about tert-butyl((3,5-dimethoxycyclohexa-2,5-dien-1-yl)methoxy)diphenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(3,5-dimethoxycyclohexa-2,5-dien-1-yl)methanol (90612-16-1) + tert-butylchlorodiphenylsilane (58479-61-1) → tert-butyl((3,5-dimethoxycyclohexa-2,5-dien-1-yl)methoxy)diphenylsilane (130472-03-6)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; for 20h; Ambient temperature;

Reference yield:

3,5-dimethoxycyclohexa-2,5-diene-1-carboxylic acid (24941-58-0) → tert-butyl((3,5-dimethoxycyclohexa-2,5-dien-1-yl)methoxy)diphenylsilane (130472-03-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / LiAlH₄ / diethyl ether

2: 96 percent / imidazole / dimethylformamide / 20 h / Ambient temperature

With 1H-imidazole; lithium aluminium tetrahydride; In diethyl ether; N,N-dimethyl-formamide;

Reference yield: 100.0%

tert-butyl((3,5-dimethoxycyclohexa-2,5-dien-1-yl)methoxy)diphenylsilane (130472-03-6) → 5-({[tert-butyl(diphenyl)silyl]oxy}methyl)cyclohexane-1,3-dione (1366053-40-8)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; for 3h; chemoselective reaction; Inert atmosphere;

DOI:10.1016/j.tet.2017.01.042

upstream raw materials:

(3,5-dimethoxycyclohexa-2,5-dien-1-yl)methanol

tert-butylchlorodiphenylsilane

3,5-dimethoxycyclohexa-2,5-diene-1-carboxylic acid

Downstream raw materials:

5-({[tert-butyl(diphenyl)silyl]oxy}methyl)cyclohexane-1,3-dione