C₂₂H₁₆INO

Base Information

• Chemical Name: C₂₂H₁₆INO
• CAS No.: 1207518-13-5
• Molecular Formula: C₂₂H₁₆INO
• Molecular Weight: 437.28
• Mol file: 1207518-13-5.mol

Synonyms:C₂₂H₁₆INO

Chemical Property of C₂₂H₁₆INO

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₂₂H₁₆INO

There total 1 articles about C₂₂H₁₆INO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-Iodobenzoic acid (88-67-5) + 4-methyl-2-(phenylethynyl)aniline (13141-44-1) → C22H16INO (1207518-13-5)

Guidance literature:

With tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; In dichloromethane; water; for 5h;

DOI:10.1055/S-0029-1218298

Reference yield: 87.0%

C22H16INO (1207518-13-5) → C22H17NO (1207518-21-5)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium formate; In water; N,N-dimethyl-formamide; at 120 ℃; for 4.2h; regioselective reaction;

DOI:10.1055/S-0029-1218298

upstream raw materials:

2-Iodobenzoic acid

4-methyl-2-(phenylethynyl)aniline

Downstream raw materials:

C₂₂H₁₇NO