2-(4-hydroxy-phenyl)-3-methyl-1-[10-(pentane-1-sulfonyl)-decyl]-1H-indole-5-carboxylic acid amide

Base Information

• Chemical Name: 2-(4-hydroxy-phenyl)-3-methyl-1-[10-(pentane-1-sulfonyl)-decyl]-1H-indole-5-carboxylic acid amide
• CAS No.: 528852-79-1
• Molecular Formula: C₃₁H₄₄N₂O₄S
• Molecular Weight: 540.767

Synonyms:2-(4-hydroxy-phenyl)-3-methyl-1-[10-(pentane-1-sulfonyl)-decyl]-1H-indole-5-carboxylic acid amide

Chemical Property of 2-(4-hydroxy-phenyl)-3-methyl-1-[10-(pentane-1-sulfonyl)-decyl]-1H-indole-5-carboxylic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-hydroxy-phenyl)-3-methyl-1-[10-(pentane-1-sulfonyl)-decyl]-1H-indole-5-carboxylic acid amide

There total 4 articles about 2-(4-hydroxy-phenyl)-3-methyl-1-[10-(pentane-1-sulfonyl)-decyl]-1H-indole-5-carboxylic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5-carbamoyl-2-(4-methoxyphenyl)-3-methyl-1-[10-(pentylsulfonyl)decyl]indole (528853-02-3) → 2-(4-hydroxy-phenyl)-3-methyl-1-[10-(pentane-1-sulfonyl)-decyl]-1H-indole-5-carboxylic acid amide (528852-79-1)

Guidance literature:

With boron tribromide; In dichloromethane; at -20 - 20 ℃;

DOI:10.1016/S0968-0896(02)00306-1

Reference yield:

2-bromo-1-(4-methoxyphenyl)-1-propanone (21086-33-9) → 2-(4-hydroxy-phenyl)-3-methyl-1-[10-(pentane-1-sulfonyl)-decyl]-1H-indole-5-carboxylic acid amide (528852-79-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 22 percent / N,N-dimethyl-aniline; xylene / 3 h / Heating

2.1: NaH / dimethylformamide / 0 - 5 °C

2.2: 80 percent / dimethylformamide / 0 - 20 °C

3.1: 86 percent / BBr₃ / CH₂Cl₂ / -20 - 20 °C

With boron tribromide; sodium hydride; In dichloromethane; N,N-dimethyl-aniline; N,N-dimethyl-formamide; xylene;

DOI:10.1016/S0968-0896(02)00306-1

Reference yield:

4-aminobenzamide (2835-68-9) → 2-(4-hydroxy-phenyl)-3-methyl-1-[10-(pentane-1-sulfonyl)-decyl]-1H-indole-5-carboxylic acid amide (528852-79-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 22 percent / N,N-dimethyl-aniline; xylene / 3 h / Heating

2.1: NaH / dimethylformamide / 0 - 5 °C

2.2: 80 percent / dimethylformamide / 0 - 20 °C

3.1: 86 percent / BBr₃ / CH₂Cl₂ / -20 - 20 °C

With boron tribromide; sodium hydride; In dichloromethane; N,N-dimethyl-aniline; N,N-dimethyl-formamide; xylene;

DOI:10.1016/S0968-0896(02)00306-1

upstream raw materials:

5-carbamoyl-2-(4-methoxyphenyl)-3-methyl-1-[10-(pentylsulfonyl)decyl]indole

2-bromo-1-(4-methoxyphenyl)-1-propanone

4-aminobenzamide

5-carbamoyl-2-(4-methoxyphenyl)-3-methylindole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 528852-79-1 2-(4-hydroxy-phenyl)-3-methyl-1-[10-(pentane-1-sulfonyl)-decyl]-1H-indole-5-carboxylic acid amide

Send

Send

Metric Ton KG G Pound L ML

Send

Send