2-isobutyl-2-phenyl phenylacetic acid

Base Information

Chemical Name:2-isobutyl-2-phenyl phenylacetic acid
CAS No.:25209-47-6
Molecular Formula:C₁₈H₂₀O₂
Molecular Weight:268.356
Hs Code.:

Synonyms:2-isobutyl-2-phenyl phenylacetic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-isobutyl-2-phenyl phenylacetic acid

Chemical Property:

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Technology Process of 2-isobutyl-2-phenyl phenylacetic acid

There total 4 articles about 2-isobutyl-2-phenyl phenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78-77-3
Isobutyl bromide

: 117-34-0
2,2-diphenylacetic acid

: 25209-47-6
2-isobutyl-2-phenyl phenylacetic acid

Guidance literature:: 2,2-diphenylacetic acid; With lithium diisopropyl amide; In tetrahydrofuran; at 0 - 45 ℃; for 1h; Inert atmosphere;

Isobutyl bromide; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.8b02856

Reference yield:

: 25209-35-2
4-methyl-2, 2-diphenylpent-4-enoic acid

: 25209-47-6
2-isobutyl-2-phenyl phenylacetic acid

Guidance literature:: With ethanol; platinum; Hydrogenation;
DOI:10.1021/ja01167a022

Reference yield:

: 117-34-0
2,2-diphenylacetic acid

: 25209-47-6
2-isobutyl-2-phenyl phenylacetic acid

Guidance literature:: 2,2-diphenylacetic acid; With lithium diisopropyl amide; In tetrahydrofuran; at 0 - 20 ℃; for 4h; Inert atmosphere;

In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.0c02216