2-D08

Base Information

Chemical Name:2-D08
CAS No.:144707-18-6
Molecular Formula:C₁₅H₁₀O₅
Molecular Weight:270.241
Hs Code.:2932990090
Mol file:144707-18-6.mol

Synonyms:2′,3′,4′ -trihydroxyflavone

Suppliers and Price of 2-D08

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-D08
5mg
$ 165.00

TRC
2-D08
1mg
$ 50.00

DC Chemicals
2-D08 >98%
100 mg
$ 550.00

DC Chemicals
2-D08 >98%
1 g
$ 1900.00

ChemScene
2-D08 99.04%
100mg
$ 590.00

ChemScene
2-D08 99.04%
10mg
$ 100.00

ChemScene
2-D08 99.04%
5mg
$ 60.00

ChemScene
2-D08 99.04%
25mg
$ 210.00

ChemScene
2-D08 99.04%
50mg
$ 340.00

Cayman Chemical
2-D08 ≥98%
25mg
$ 250.00

Total 11 raw suppliers

Chemical Property of 2-D08

Chemical Property:

Boiling Point:517.9±50.0 °C(Predicted)
PKA:7.45±0.40(Predicted)
Density:1.548±0.06 g/cm3(Predicted)
Storage Temp.:2-8°C
Solubility.:≥74.6 mg/mL in DMSO; ≥1.76 mg/mL in EtOH with gentle warming and ultrasonic; insoluble in H2O

Purity/Quality:

97% ^*data from raw suppliers

2-D08 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-D08 has been used as a small ubiquitin-like modifier (SUMO)ylation inhibitor.

Technology Process of 2-D08

There total 9 articles about 2-D08 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 7143-46-6
2',3',4'-Trimethoxyflavone

: 144707-18-6
2′,3′,4′ -trihydroxyflavone

Guidance literature:: With boron tribromide; In dichloromethane; for 48h; Inert atmosphere;
DOI:10.1016/j.bmcl.2014.01.010

Reference yield:

: 573-11-5
2,3,4-Trimethoxy-benzoic acid

: 144707-18-6
2′,3′,4′ -trihydroxyflavone

Guidance literature:: Multi-step reaction with 4 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 18 h / 20 °C / Inert atmosphere

2: pyridine; potassium hydroxide / 2 h / 50 °C / Inert atmosphere

3: sulfuric acid / acetic acid / 1 h / 110 °C / Inert atmosphere

4: boron tribromide / dichloromethane / 48 h / Inert atmosphere

With pyridine; dmap; sulfuric acid; boron tribromide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; potassium hydroxide; In dichloromethane; acetic acid; 2: |Wessely-Moser Rearrangement;
DOI:10.1016/j.bmcl.2014.01.010

Reference yield:

: 1563185-99-8
C₁₈H₁₈O₆

: 144707-18-6
2′,3′,4′ -trihydroxyflavone

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine; potassium hydroxide / 2 h / 50 °C / Inert atmosphere

2: sulfuric acid / acetic acid / 1 h / 110 °C / Inert atmosphere

3: boron tribromide / dichloromethane / 48 h / Inert atmosphere

With pyridine; sulfuric acid; boron tribromide; potassium hydroxide; In dichloromethane; acetic acid; 1: |Wessely-Moser Rearrangement;
DOI:10.1016/j.bmcl.2014.01.010