Technology Process of 5-amino-2-butoxybenzoic acid methyl ester
There total 3 articles about 5-amino-2-butoxybenzoic acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate; nickel(II) chloride hexahydrate;
In
methanol;
at 20 ℃;
for 2h;
DOI:10.1016/j.ejmech.2017.04.050
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 70 percent / nitric acid; sulfuric acid / 1 h / 20 °C
2: H2 / Pd/C / tetrahydrofuran / 6 h / 20 °C / 760 Torr
With
sulfuric acid; hydrogen; nitric acid;
palladium on activated charcoal;
In
tetrahydrofuran;
DOI:10.1021/ja064218i
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 80 °C
1.2: 4 h / 80 °C
2.1: nickel(II) chloride hexahydrate; sodium tetrahydroborate / methanol / 2 h / 20 °C
With
sodium tetrahydroborate; nickel(II) chloride hexahydrate; potassium carbonate;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2017.04.050
