2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE

Base Information

• Chemical Name: 2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE
• CAS No.: 61310-39-2
• Molecular Formula: C₉H₈N₄O
• Molecular Weight: 188.189
• Hs Code.: 2933990090
• Mol file: 61310-39-2.mol

Synonyms:4(1H)-Pyrimidinone,6-amino-2-(4-pyridinyl)- (9CI); 6-Amino-2-(pyridin-4-yl)pyrimidin-4-ol

Chemical Property of 2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE

Chemical Property:

• Boiling Point: 364.8±52.0 °C(Predicted)
• PKA: 7.93±0.50(Predicted)
• PSA: 84.92000
• Density: 1.46±0.1 g/cm3(Predicted)
• LogP: 1.40760

Purity/Quality:

99.90% ^*data from raw suppliers

6-amino-2-(pyridin-4-yl)pyrimidin-4(1H)-one 95%-98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE

There total 2 articles about 2-(4-PYRIDYL)-4-AMINO-6-HYDROXY PYRIMIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

→ 6-amino-2-pyridin-4-yl-3H-pyrimidin-4-one (61310-39-2)

Guidance literature:

Reference yield:

4-amidinopyridine hydrochloride (6345-27-3,42518-06-9,61875-64-7) + ethyl 2-cyanoacetate (105-56-6) → 6-amino-2-pyridin-4-yl-3H-pyrimidin-4-one (61310-39-2)

Guidance literature:

With sodium methylate; acetic acid; In ethanol; water;

upstream raw materials:

4-amidinopyridine hydrochloride

ethyl 2-cyanoacetate