(4-Amino-phenyl)-acetic acid p-tolyl ester; compound with trifluoro-acetic acid

Base Information

Chemical Name:(4-Amino-phenyl)-acetic acid p-tolyl ester; compound with trifluoro-acetic acid
CAS No.:139631-76-8
Molecular Formula:C₂HF₃O₂*C₁₅H₁₅NO₂
Molecular Weight:355.314
Hs Code.:

Synonyms:(4-Amino-phenyl)-acetic acid p-tolyl ester; compound with trifluoro-acetic acid

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Chemical Property of (4-Amino-phenyl)-acetic acid p-tolyl ester; compound with trifluoro-acetic acid

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Technology Process of (4-Amino-phenyl)-acetic acid p-tolyl ester; compound with trifluoro-acetic acid

There total 4 articles about (4-Amino-phenyl)-acetic acid p-tolyl ester; compound with trifluoro-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 106-44-5
p-cresol

: 139631-76-8
(4-Amino-phenyl)-acetic acid p-tolyl ester; compound with trifluoro-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) / ethyl acetate / 24 h / Ambient temperature

2: CH₂Cl₂ / 1 h / Ambient temperature

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; ethyl acetate;
DOI:10.1021/ja00035a057

Reference yield:

: 1197-55-3
4-aminophenylacetic acid

: 139631-76-8
(4-Amino-phenyl)-acetic acid p-tolyl ester; compound with trifluoro-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dimethylformamide

2: 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) / ethyl acetate / 24 h / Ambient temperature

3: CH₂Cl₂ / 1 h / Ambient temperature

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/ja00035a057

Reference yield:

: 81196-09-0
2-(4-(tert-butoxycarbonylamino)phenyl)acetic acid

: 139631-76-8
(4-Amino-phenyl)-acetic acid p-tolyl ester; compound with trifluoro-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) / ethyl acetate / 24 h / Ambient temperature

2: CH₂Cl₂ / 1 h / Ambient temperature

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; ethyl acetate;
DOI:10.1021/ja00035a057