ethyl 2-(4-hydroxy-3,5-diiodophenyl)-2-oxoacetate

Base Information

• Chemical Name: ethyl 2-(4-hydroxy-3,5-diiodophenyl)-2-oxoacetate
• CAS No.: 1093730-40-5
• Molecular Formula: C₁₀H₈I₂O₄
• Molecular Weight: 445.98
• Mol file: 1093730-40-5.mol

Synonyms:ethyl 2-(4-hydroxy-3,5-diiodophenyl)-2-oxoacetate

Chemical Property of ethyl 2-(4-hydroxy-3,5-diiodophenyl)-2-oxoacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of ethyl 2-(4-hydroxy-3,5-diiodophenyl)-2-oxoacetate

There total 1 articles about ethyl 2-(4-hydroxy-3,5-diiodophenyl)-2-oxoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-hydroxy-alpha-oxobenzeneacetic acid ethyl ester (70080-54-5) → ethyl 2-(4-hydroxy-3,5-diiodophenyl)-2-oxoacetate (1093730-40-5)

Guidance literature:

With Iodine monochloride; acetic acid; at 20 - 60 ℃; for 3h;

DOI:10.1080/00397910802369554

Reference yield: 74.0%

ethyl 2-(4-hydroxy-3,5-diiodophenyl)-2-oxoacetate (1093730-40-5) → 2-(4-hydroxy-3,5diiodophenyl)-2-oxoacetic acid (76590-55-1)

Guidance literature:

ethyl 2-(4-hydroxy-3,5-diiodophenyl)-2-oxoacetate; With potassium hydroxide; water; In tetrahydrofuran; at 5 - 20 ℃;

With acetic acid; In tert-butyl methyl ether; at 20 ℃; for 18h;

DOI:10.1080/00397910802369554

upstream raw materials:

4-hydroxy-alpha-oxobenzeneacetic acid ethyl ester

Downstream raw materials:

2-(4-hydroxy-3,5diiodophenyl)-2-oxoacetic acid

Refernces