Technology Process of 6-ethoxy-1-benzyl-7-methoxy-3,4-dihydro-isoquinoline
There total 7 articles about 6-ethoxy-1-benzyl-7-methoxy-3,4-dihydro-isoquinoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 94 percent / K2CO3 / ethanol / 5 h / Heating
2: 88 percent / NH4OAc; AcOH / 4 h / Heating
3: 63 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 2 h / Heating
4: 68 percent / 5percent aq. NaOH / CH2Cl2 / 2 h / 20 °C
5: 97 percent / conc. HCl / ethanol / 4 h / Heating
6: 60 percent / K2CO3 / acetone / 10 h / Heating
7: POCl3 / CH2Cl2 / 3 h / Heating
With
hydrogenchloride; lithium aluminium tetrahydride; ammonium acetate; potassium carbonate; acetic acid; trichlorophosphate;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane; acetone;
4: Schotten-Baumann reaction / 7: Bischler-Napieralski cyclodehydration;
DOI:10.1021/jm020831a
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 63 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 2 h / Heating
2: 68 percent / 5percent aq. NaOH / CH2Cl2 / 2 h / 20 °C
3: 97 percent / conc. HCl / ethanol / 4 h / Heating
4: 60 percent / K2CO3 / acetone / 10 h / Heating
5: POCl3 / CH2Cl2 / 3 h / Heating
With
hydrogenchloride; lithium aluminium tetrahydride; potassium carbonate; trichlorophosphate;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane; acetone;
2: Schotten-Baumann reaction / 5: Bischler-Napieralski cyclodehydration;
DOI:10.1021/jm020831a
