1-(6-METHYL-PYRIDIN-2-YL)-ETHYLAMINE

Base Information

• Chemical Name: 1-(6-METHYL-PYRIDIN-2-YL)-ETHYLAMINE
• CAS No.: 58088-67-8
• Molecular Formula: C8H12N2
• Molecular Weight: 136.197
• Hs Code.: 2933399090
• Mol file: 58088-67-8.mol

Synonyms:AB1549

Chemical Property of 1-(6-METHYL-PYRIDIN-2-YL)-ETHYLAMINE

Chemical Property:

• Vapor Pressure: 0.265mmHg at 25°C
• Refractive Index: 1.532
• Boiling Point: 281.4 °C at 760 mmHg
• PKA: 9.10±0.50(Predicted)
• Flash Point: 98 °C
• PSA: 38.91000
• Density: 1 g/cm³
• LogP: 2.11000

Purity/Quality:

98%min ^*data from raw suppliers

1-(6-methylpyridin-2-yl)ethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(6-METHYL-PYRIDIN-2-YL)-ETHYLAMINE

There total 2 articles about 1-(6-METHYL-PYRIDIN-2-YL)-ETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

2-acetyl-6-methylpyridine (6940-57-4) → 1-(6-methylpyridin-2-yl)ethan-1-amine (58088-67-8)

Guidance literature:

With ammonium acetate; sodium cyanoborohydride; In methanol; at 20 ℃;

Reference yield:

→ 1-(6-methylpyridin-2-yl)ethan-1-amine (58088-67-8)

Guidance literature:

entspr. 2-(1-Hydroxyiminoethyl)-Verb., Zn/NH4OAc/cc. NH3/A.;

Reference yield: 65.0%

methyl 3-(pyridin-4-yl)-1-trityl-1,7-dihydroimidazo[4,5-f]indazole-6-carboxylate + 1-(6-methylpyridin-2-yl)ethan-1-amine (58088-67-8) → N-(1-(6-methylpyridin-2-yl)ethyl)-3-(pyridin-4-yl)-1-trityl-1,7-dihydroimidazo[4,5-f]indazole-6-carboxamide

Guidance literature:

In 1-methyl-pyrrolidin-2-one; at 120 ℃; for 2h; Microwave irradiation;

upstream raw materials:

2-acetyl-6-methylpyridine

Refernces