5-(4-chlorobenzylidene)-3-(4-chlorophenyl)-2-(4-dimethylaminophenyl)-4-thiazolidinone

Base Information

Chemical Name:5-(4-chlorobenzylidene)-3-(4-chlorophenyl)-2-(4-dimethylaminophenyl)-4-thiazolidinone
CAS No.:1353992-39-8
Molecular Formula:C₂₄H₂₀Cl₂N₂OS
Molecular Weight:455.408
Hs Code.:

Synonyms:5-(4-chlorobenzylidene)-3-(4-chlorophenyl)-2-(4-dimethylaminophenyl)-4-thiazolidinone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4-chlorobenzylidene)-3-(4-chlorophenyl)-2-(4-dimethylaminophenyl)-4-thiazolidinone

Chemical Property:

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Technology Process of 5-(4-chlorobenzylidene)-3-(4-chlorophenyl)-2-(4-dimethylaminophenyl)-4-thiazolidinone

There total 4 articles about 5-(4-chlorobenzylidene)-3-(4-chlorophenyl)-2-(4-dimethylaminophenyl)-4-thiazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 93515-32-3
(Z)-3-(4-Chloro-phenyl)-2-mercapto-acrylic acid

: 106-47-8
4-chloro-aniline

: 100-10-7
4-dimethylamino-benzaldehyde

: 1353992-39-8
5-(4-chlorobenzylidene)-3-(4-chlorophenyl)-2-(4-dimethylaminophenyl)-4-thiazolidinone

Guidance literature:: In benzene; for 24h; Reflux;
DOI:10.1016/j.tetlet.2011.11.095

Reference yield:

: 81154-19-0,81154-18-9
(Z)-5-(4-chlorobenzylidene)-2-sulfanylidenethiazolidin-4-one

: 1353992-39-8
5-(4-chlorobenzylidene)-3-(4-chlorophenyl)-2-(4-dimethylaminophenyl)-4-thiazolidinone

Guidance literature:: Multi-step reaction with 2 steps

1: water; sodium hydroxide / 0.5 h / Reflux

2: benzene / 24 h / Reflux

With water; sodium hydroxide; In benzene;
DOI:10.1016/j.tetlet.2011.11.095