(-)-(S)-5-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-3-methoxybenzamide

Base Information

Chemical Name:(-)-(S)-5-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-3-methoxybenzamide
CAS No.:128600-22-6
Molecular Formula:C15H21 Br N2 O3
Molecular Weight:357.24
Hs Code.:
DSSTox Substance ID:DTXSID20451494
Nikkaji Number:J338.984G
Wikidata:Q82271550
Mol file:128600-22-6.mol

Synonyms:128600-22-6;(-)-(S)-5-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-HYDROXY-3-METHOXYBENZAMIDE;5-bromo-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-3-methoxybenzamide;(S)-5-Bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-methoxybenzamide;Benzamide, 5-bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-3-methoxy-;DFLB;DTXSID20451494;UDVCHWOEHQSXMW-NSHDSACASA-N;AG-D-58861;5-Bromo-2-hydroxy-3-methoxy-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]benzamide

Suppliers and Price of (-)-(S)-5-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-3-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(-)-(S)-5-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-HYDROXY-3-METHOXYBENZAMIDE 95.00%
5MG
$ 498.44

Total 5 raw suppliers

Chemical Property of (-)-(S)-5-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-3-methoxybenzamide

Chemical Property:

Boiling Point:422.9 °C at 760 mmHg
Flash Point:209.6 °C
PSA：61.80000
Density:1.364 g/cm³
LogP:2.70620
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:356.07356
Heavy Atom Count:21
Complexity:356

Purity/Quality:

99% ^*data from raw suppliers

(-)-(S)-5-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-HYDROXY-3-METHOXYBENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCCC1CNC(=O)C2=C(C(=CC(=C2)Br)OC)O
Isomeric SMILES:CCN1CCC[C@H]1CNC(=O)C2=C(C(=CC(=C2)Br)OC)O

Technology Process of (-)-(S)-5-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-3-methoxybenzamide

There total 5 articles about (-)-(S)-5-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-3-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: (S)-(-)-5-bromo-N-((1-ethyl-2-pyrrolidinyl)methyl)-2,3-dimethoxybenzamide hydrochloride

: 128600-22-6
(-)-(S)-5-bromo-N-<(1-ethyl-2-pyrrolidinyl)methyl>-2-hydroxy-3-methoxybenzamide

Guidance literature:: With boron tribromide; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1002/(SICI)1099-1344(20000330)43:4<331::AID-JLCR320>3.0.CO;2-H

Reference yield:

: 877-22-5
3-methoxysalicylic acid

: 128600-22-6
(-)-(S)-5-bromo-N-<(1-ethyl-2-pyrrolidinyl)methyl>-2-hydroxy-3-methoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.70 g / bromine; pyridine / CHCl₃ / 1 h

2: N,N'-dicyclohexylcarbodiimide / CHCl₃

With pyridine; bromine; dicyclohexyl-carbodiimide; In chloroform;