Tert-butyl 3-bromo-4-oxopiperidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 3-bromo-4-oxopiperidine-1-carboxylate
CAS No.:188869-05-8
Molecular Formula:C10H16BrNO3
Molecular Weight:278.146
Hs Code.:2933399090
European Community (EC) Number:692-215-7
DSSTox Substance ID:DTXSID60443510
Mol file:188869-05-8.mol

Synonyms:188869-05-8;tert-butyl 3-bromo-4-oxopiperidine-1-carboxylate;N-Boc-3-bromo-4-oxopiperidine;3-Bromo-4-Oxo-Piperidine-1-Carboxylic acid Tert-Butyl Ester;N-BOC-3-BROMO-4-PIPERIDONE;1-Piperidinecarboxylic acid, 3-bromo-4-oxo-, 1,1-dimethylethyl ester;1-tert-Butoxycarbonyl-3-bromo-4-oxopiperidine;MFCD06738530;1-BOC-3-BROMO-4-OXO-PIPERIDINE;Tert-butyl 3-bromo-4-oxo-piperidine-1-carboxylate;C10H16BrNO3;1-TERT-BUTYLOXYCARBONYL-3-BROMO-4-OXOPIPERIDINE;3-BROMO-4-OXOPIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;SCHEMBL166445;DTXSID60443510;RGWGRRBHQUREDE-UHFFFAOYSA-N;1-Piperidinecarboxylicacid,3-bromo-4-oxo-,1,1-dimethylethylester;AB1131;AKOS015838312;AB27321;CS-W001487;DS-0375;AC-28246;SY005836;n-tert-butoxycarbonyl-3-bromo-4-piperidone;A4175;AM20090104;BB 0260558;FT-0647702;1-tert-Butoxycarbonyl-3-bromopiperidin-4-one;EN300-94662;tert-butyl3-bromo-4-oxopiperidine-1-carboxylate;tert-Butyl 3-bromo-4-oxo-1-piperidinecarboxylate;J-524527;1,1-dimethylethyl 3-bromo-4-oxo-1-piperidinecarboxylate;1,1-dimethylethyl 3-bromo-4-oxopiperidine-1-carboxylate;1-N-Boc-3-bromopiperid-4-one tert-Butyl 3-bromo-4-oxopiperidine-1-carboxylate

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Chemical Property of Tert-butyl 3-bromo-4-oxopiperidine-1-carboxylate

Chemical Property:

Appearance/Colour:Light yellow solid
Vapor Pressure:0mmHg at 25°C
Refractive Index:1.519
Boiling Point:333.3 °C at 760 mmHg
PKA:-3.35±0.40(Predicted)
Flash Point:155.4 °C
PSA：46.61000
Density:1.422 g/cm³
LogP:1.89770
Storage Temp.:2-8°C(protect from light)
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:277.03136
Heavy Atom Count:15
Complexity:272

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(=O)C(C1)Br

Technology Process of Tert-butyl 3-bromo-4-oxopiperidine-1-carboxylate

There total 10 articles about Tert-butyl 3-bromo-4-oxopiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 118652-88-3
3-bromo-piperidin-4-one-hydrobromide

: 188869-05-8
tert-butyl 3-bromo-4-oxo-piperidine-1-carboxylate

Guidance literature:: 3-bromo-piperidin-4-one-hydrobromide; With N-ethyl-N,N-diisopropylamine; dmap; In tetrahydrofuran; at 20 ℃; for 0.166667h;

di-tert-butyl dicarbonate; In tetrahydrofuran; at 20 ℃;