17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-(1H-imidazol-1-yl)methyl morphinan

Base Information

Chemical Name:17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-(1H-imidazol-1-yl)methyl morphinan
CAS No.:1032281-18-7
Molecular Formula:C₃₁H₃₅N₃O₃
Molecular Weight:497.637
Hs Code.:

Synonyms:17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-(1H-imidazol-1-yl)methyl morphinan

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-(1H-imidazol-1-yl)methyl morphinan

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Technology Process of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-(1H-imidazol-1-yl)methyl morphinan

There total 1 articles about 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-(1H-imidazol-1-yl)methyl morphinan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 288-32-4
1H-imidazole

: 1032281-09-6
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-(p-toluenesulfonylmethyl) morphinan

: 1032281-18-7
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-(1H-imidazol-1-yl)methyl morphinan

Guidance literature:: 1H-imidazole; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-(p-toluenesulfonylmethyl) morphinan; In N,N-dimethyl-formamide; at 20 - 50 ℃; for 7h;