Technology Process of tert-Butyl-diphenyl-((2S,4S)-2,4,6-trimethyl-hept-6-enyloxy)-silane
There total 6 articles about tert-Butyl-diphenyl-((2S,4S)-2,4,6-trimethyl-hept-6-enyloxy)-silane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(I) bromide dimethylsulfide complex;
In
tetrahydrofuran;
at -15 ℃;
for 2h;
DOI:10.1021/ol035846x
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: n-BuLi / H2O; tetrahydrofuran
2.1: lithium tri-sec-butylborohydride / 2 h / -90 - -60 °C
2.2: hexamethylphosphoric triamide / 12 h / -78 °C
3.1: i-Bu2AlH / 2 h / -78 °C
4.1: NaBH4 / methanol / 20 °C
5.1: PPh3; I2; imidazole / benzene / 1 h / 20 °C
6.1: CuBr*SMe2 / tetrahydrofuran / 2 h / -15 °C
With
1H-imidazole; sodium tetrahydroborate; n-butyllithium; copper(I) bromide dimethylsulfide complex; iodine; L-Selectride; diisobutylaluminium hydride; triphenylphosphine;
In
tetrahydrofuran; methanol; water; benzene;
1.1: Horner-Wadsworth-Emmons olefination;
DOI:10.1021/ol035846x
- Guidance literature:
-
Multi-step reaction with 3 steps
1: NaBH4 / methanol / 20 °C
2: PPh3; I2; imidazole / benzene / 1 h / 20 °C
3: CuBr*SMe2 / tetrahydrofuran / 2 h / -15 °C
With
1H-imidazole; sodium tetrahydroborate; copper(I) bromide dimethylsulfide complex; iodine; triphenylphosphine;
In
tetrahydrofuran; methanol; benzene;
DOI:10.1021/ol035846x
