ethyl (6-amino-4-{[2-(4-methoxyphenyl)-2-oxoethyl]amino}-5-nitropyridin-2-yl)carbamate

Base Information

Chemical Name:ethyl (6-amino-4-{[2-(4-methoxyphenyl)-2-oxoethyl]amino}-5-nitropyridin-2-yl)carbamate
CAS No.:82585-81-7
Molecular Formula:C17H19 N5 O6
Molecular Weight:389.368
Hs Code.:

Synonyms:NSC330775

Suppliers and Price of ethyl (6-amino-4-{[2-(4-methoxyphenyl)-2-oxoethyl]amino}-5-nitropyridin-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 3 raw suppliers

Chemical Property of ethyl (6-amino-4-{[2-(4-methoxyphenyl)-2-oxoethyl]amino}-5-nitropyridin-2-yl)carbamate

Chemical Property:

Vapor Pressure:9.25E-16mmHg at 25°C
Boiling Point:629.6°Cat760mmHg
Flash Point:334.5°C
Density:1.43g/cm³

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl (6-amino-4-{[2-(4-methoxyphenyl)-2-oxoethyl]amino}-5-nitropyridin-2-yl)carbamate

There total 3 articles about ethyl (6-amino-4-{[2-(4-methoxyphenyl)-2-oxoethyl]amino}-5-nitropyridin-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 82585-68-0
{6-Amino-4-[2-[(Z)-hydroxyimino]-2-(4-methoxy-phenyl)-ethylamino]-5-nitro-pyridin-2-yl}-carbamic acid ethyl ester

: 82585-81-7
{6-Amino-4-[2-(4-methoxy-phenyl)-2-oxo-ethylamino]-5-nitro-pyridin-2-yl}-carbamic acid ethyl ester

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 60 ℃; for 20h;
DOI:10.1021/jm00351a008

Reference yield:

: 6506-86-1
ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate

: 82585-81-7
{6-Amino-4-[2-(4-methoxy-phenyl)-2-oxo-ethylamino]-5-nitro-pyridin-2-yl}-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 55 percent / Et₃N / ethanol / 4 h / 75 °C

2: 53 percent / 1N aq. HCl / dioxane / 20 h / 60 °C

With hydrogenchloride; triethylamine; In 1,4-dioxane; ethanol;
DOI:10.1021/jm00351a008

Reference yield:

: 92561-08-5
2-Amino-1-(4-methoxy-phenyl)-ethanone oxime; hydrochloride

: 82585-81-7
{6-Amino-4-[2-(4-methoxy-phenyl)-2-oxo-ethylamino]-5-nitro-pyridin-2-yl}-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 55 percent / Et₃N / ethanol / 4 h / 75 °C

2: 53 percent / 1N aq. HCl / dioxane / 20 h / 60 °C

With hydrogenchloride; triethylamine; In 1,4-dioxane; ethanol;
DOI:10.1021/jm00351a008