(3S,5R,8R,10S)-6-Acetoxy-7-benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-3,5,8,10-tetramethyl-undecanoic acid methyl ester

Base Information

Chemical Name:(3S,5R,8R,10S)-6-Acetoxy-7-benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-3,5,8,10-tetramethyl-undecanoic acid methyl ester
CAS No.:545445-73-6
Molecular Formula:C₃₀H₅₂O₇SSi
Molecular Weight:584.89
Hs Code.:

Synonyms:(3S,5R,8R,10S)-6-Acetoxy-7-benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-3,5,8,10-tetramethyl-undecanoic acid methyl ester

Suppliers and Price of (3S,5R,8R,10S)-6-Acetoxy-7-benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-3,5,8,10-tetramethyl-undecanoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,5R,8R,10S)-6-Acetoxy-7-benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-3,5,8,10-tetramethyl-undecanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,5R,8R,10S)-6-Acetoxy-7-benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-3,5,8,10-tetramethyl-undecanoic acid methyl ester

There total 14 articles about (3S,5R,8R,10S)-6-Acetoxy-7-benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-3,5,8,10-tetramethyl-undecanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 108-24-7
acetic anhydride

: 197016-10-7
(3S,5R,8R,10S)-7-Benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-6-hydroxy-3,5,8,10-tetramethyl-undecanoic acid methyl ester

: 545445-73-6
(3S,5R,8R,10S)-6-Acetoxy-7-benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-3,5,8,10-tetramethyl-undecanoic acid methyl ester

Guidance literature:: With pyridine; at 25 ℃;
DOI:10.1002/anie.199717451

Reference yield:

: 873-55-2
sodium benzenesulfonate

: 545445-73-6
(3S,5R,8R,10S)-6-Acetoxy-7-benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-3,5,8,10-tetramethyl-undecanoic acid methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 91 percent / various solvent(s) / 130 °C

2: 91 percent / K₂CO₃, MeOH / 25 °C

3: 99 percent / imidazole, DMAP / dimethylformamide / 50 °C

4: 97 percent / BuLi / tetrahydrofuran / -78 °C

5: 90 percent / pyridine / 25 °C

With pyridine; 1H-imidazole; methanol; dmap; n-butyllithium; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/anie.199717451

Reference yield:

: 197015-99-9
(3S,5R)-3,5-Dimethyl-6-oxo-hexanoic acid methyl ester

: 545445-73-6
(3S,5R,8R,10S)-6-Acetoxy-7-benzenesulfonyl-11-(tert-butyl-dimethyl-silanyloxy)-3,5,8,10-tetramethyl-undecanoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / BuLi / tetrahydrofuran / -78 °C

2: 90 percent / pyridine / 25 °C

With pyridine; n-butyllithium; In tetrahydrofuran;
DOI:10.1002/anie.199717451