Technology Process of (2S)-2-<(tert-butyldiphenylsilyl)oxy>-(Z,Z)-3,6-dodecadien-1-al
There total 6 articles about (2S)-2-<(tert-butyldiphenylsilyl)oxy>-(Z,Z)-3,6-dodecadien-1-al which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
4 A molecular sieve; sodium acetate; pyridinium chlorochromate;
In
dichloromethane;
for 0.5h;
Ambient temperature;
DOI:10.1021/jo951061w
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) lithium bis(trimethylsilyl)amide / 1) THF, toluene, 0 deg C, 30 min; 2) THF, toluene, 0 deg C, 2 h
2: 83 percent / aq. HCl / methanol / 2 h / 0 °C
3: 75 percent / 4-(dimethylamino)pyridine / CH2Cl2 / 5 h / Ambient temperature
4: 81 percent / 4-(dimethylamino)pyridine / CH2Cl2 / 15 h / Ambient temperature
5: 76 percent / pyridinium p-toluenesulfonate / ethanol / 15 h / 60 °C
6: 73 percent / pyridinium chlorochromate, sodium acetate, 4 Angstroem molecular sieves / CH2Cl2 / 0.5 h / Ambient temperature
With
hydrogenchloride; dmap; 4 A molecular sieve; sodium acetate; pyridinium p-toluenesulfonate; pyridinium chlorochromate; lithium hexamethyldisilazane;
In
methanol; ethanol; dichloromethane;
DOI:10.1021/jo951061w
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 75 percent / 4-(dimethylamino)pyridine / CH2Cl2 / 5 h / Ambient temperature
2: 81 percent / 4-(dimethylamino)pyridine / CH2Cl2 / 15 h / Ambient temperature
3: 76 percent / pyridinium p-toluenesulfonate / ethanol / 15 h / 60 °C
4: 73 percent / pyridinium chlorochromate, sodium acetate, 4 Angstroem molecular sieves / CH2Cl2 / 0.5 h / Ambient temperature
With
dmap; 4 A molecular sieve; sodium acetate; pyridinium p-toluenesulfonate; pyridinium chlorochromate;
In
ethanol; dichloromethane;
DOI:10.1021/jo951061w
