Methyl 3,7:6,10-anhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-D-glycero-L-allo-4-undeculosonate

Base Information

Chemical Name:Methyl 3,7:6,10-anhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-D-glycero-L-allo-4-undeculosonate
CAS No.:122821-96-9
Molecular Formula:C₃₆H₄₄O₇Si
Molecular Weight:616.827
Hs Code.:

Synonyms:Methyl 3,7:6,10-anhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-D-glycero-L-allo-4-undeculosonate

Suppliers and Price of Methyl 3,7:6,10-anhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-D-glycero-L-allo-4-undeculosonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl 3,7:6,10-anhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-D-glycero-L-allo-4-undeculosonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl 3,7:6,10-anhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-D-glycero-L-allo-4-undeculosonate

There total 7 articles about Methyl 3,7:6,10-anhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-D-glycero-L-allo-4-undeculosonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 122821-95-8
Methyl 3,7:6,10-dianhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-4-O-(trimethylsilyl)-D-threo-L-gluco-undeconate

: 122821-96-9
Methyl 3,7:6,10-anhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-D-glycero-L-allo-4-undeculosonate

Guidance literature:: With jones' reagent; In acetone; at 0 ℃; for 0.5h;
DOI:10.1021/ja00199a031

Reference yield:

: 122821-89-0
[(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-hydroxy-3-methyl-tetrahydro-pyran-2-yl]-acetaldehyde

: 122821-96-9
Methyl 3,7:6,10-anhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-D-glycero-L-allo-4-undeculosonate

Guidance literature:: Multi-step reaction with 6 steps

1: tetrahydrofuran / 0.5 h / 0 °C

2: 85 percent / CH₂Cl₂ / 0.17 h / 0 °C

3: 1.) ozone, 2.) dimethylsulfide, triphenylphosphine / 1.) CH₂Cl₂, -78 deg C, 2 h, 2.) 3 h

4: benzene / 6 h / 25 °C

5: 72 percent / sodium hydride / tetrahydrofuran / 5 h / 25 °C

6: 69 percent / Jones' reagent / acetone / 0.5 h / 0 °C

With jones' reagent; dimethylsulfide; sodium hydride; ozone; triphenylphosphine; In tetrahydrofuran; dichloromethane; acetone; benzene;
DOI:10.1021/ja00199a031

Reference yield:

: 122821-92-5
5,9-Anhydro-7-O-benzyl-10-O-(tert-butyldiphenylsilyl)-1,2,4,8-tetradeoxy-6-C-methyl-3-O-(trimethylsilyl)-D-glycero-L-altro-dec-1-enitol

: 122821-96-9
Methyl 3,7:6,10-anhydro-8-O-benzyl-11-O-(tert-butyldiphenylsilyl)-2,5,9-trideoxy-7-C-methyl-D-glycero-L-allo-4-undeculosonate

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) ozone, 2.) dimethylsulfide, triphenylphosphine / 1.) CH₂Cl₂, -78 deg C, 2 h, 2.) 3 h

2: benzene / 6 h / 25 °C

3: 72 percent / sodium hydride / tetrahydrofuran / 5 h / 25 °C

4: 69 percent / Jones' reagent / acetone / 0.5 h / 0 °C

With jones' reagent; dimethylsulfide; sodium hydride; ozone; triphenylphosphine; In tetrahydrofuran; acetone; benzene;
DOI:10.1021/ja00199a031