rac-2-Amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(pyrrolidin-3-yloxy)phenyl]pyridine-3,5-dicarbonitrile

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Chemical Name:rac-2-Amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(pyrrolidin-3-yloxy)phenyl]pyridine-3,5-dicarbonitrile
CAS No.:1182333-43-2
Molecular Formula:C₂₇H₂₁ClN₆OS₂
Molecular Weight:545.088
Hs Code.:

Synonyms:rac-2-Amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(pyrrolidin-3-yloxy)phenyl]pyridine-3,5-dicarbonitrile

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Chemical Property of rac-2-Amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(pyrrolidin-3-yloxy)phenyl]pyridine-3,5-dicarbonitrile

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Technology Process of rac-2-Amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(pyrrolidin-3-yloxy)phenyl]pyridine-3,5-dicarbonitrile

There total 1 articles about rac-2-Amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(pyrrolidin-3-yloxy)phenyl]pyridine-3,5-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 1182334-13-9
tert-Butyl 3-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}pyrrolidine-1-carboxylate

: 1182333-43-2
rac-2-Amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(pyrrolidin-3-yloxy)phenyl]pyridine-3,5-dicarbonitrile

Guidance literature:: tert-Butyl 3-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}pyrrolidine-1-carboxylate; With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 6h;

With sodium hydrogencarbonate; In 1,4-dioxane; water;