C₂₀H₂₄N₂O₅

Base Information

• Chemical Name: C₂₀H₂₄N₂O₅
• CAS No.: 322765-40-2
• Molecular Formula: C₂₀H₂₄N₂O₅
• Molecular Weight: 372.421
• Mol file: 322765-40-2.mol

Synonyms:C₂₀H₂₄N₂O₅

Chemical Property of C₂₀H₂₄N₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₄N₂O₅

There total 1 articles about C₂₀H₂₄N₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitroveratraldehyde (55149-84-3) → C20H24N2O5 (322765-40-2)

Guidance literature:

Multi-step reaction with 7 steps

1.1: KOH / dimethylformamide; ethanol

1.2: 73 percent / Ac₂O; NaOAc / Heating

2.1: 85 percent / Fe / acetic acid; ethanol / 95 °C

3.1: 92 percent / POCl₃ / 0 - 25 °C

4.1: 100 percent / NH₄OAc / 0.67 h / Heating

5.1: 91 percent / LiAlH₄ / tetrahydrofuran / 1 h / Heating

6.1: 2.0 g / molecular sieves 4 Angstroem; trifluoroacetic acid / CH₂Cl₂ / 0 - 23 °C

7.1: 67 percent / 1-hydroxybenzotriazole monohydrate; EDCI; Et₃N / dimethylformamide / 25 h / 0 - 20 °C

With potassium hydroxide; lithium aluminium tetrahydride; 4 A molecular sieve; ammonium acetate; iron; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; trichlorophosphate; In tetrahydrofuran; ethanol; dichloromethane; acetic acid; N,N-dimethyl-formamide; 1.1: Henry reaction / 3.1: Vilsmeier formylation / 4.1: Henry reaction / 6.1: Pictet Spengler reaction;

DOI:10.1016/S0040-4020(02)00243-0

Reference yield:

C20H24N2O5 (322765-40-2) → (+/-)-5,8,9,10,11,14-hexahydro-6H-15,16-dimethoxy-7,14-diazacycloundeca[a]indene-7,13-dimethoxy-7,14-diazacycloundeca[a]indene-7,13-dicarboxylic acid 13-methyl ester 7-phenyl ester (322765-43-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 100 percent / Bellau's reagent / tetrahydrofuran / 15 h / 0 - 23 °C

2: 77 percent / NiCl₂*6H₂O; NaBH₄ / tetrahydrofuran; methanol / 0.08 h / 0 °C

3: 47 percent / CH₂Cl₂ / 48 h / Heating

With sodium tetrahydroborate; 2,4-(4-phenoxyphenyl)-1,3-dithia-2λ(5),4λ(5)-diphosphetane 2,4-disulfides; nickel dichloride; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1016/S0040-4020(02)00243-0

Reference yield:

C20H24N2O5 (322765-40-2) → 1,2-dimethoxy-5,7,8,9,10,13-hexahydro-6,13-diaza-cyclodeca[a]indene-6,12-dicarboxylic acid 12-methyl ester 6-phenyl ester

Guidance literature:

Multi-step reaction with 3 steps

1: 100 percent / Belleau's reagent / tetrahydrofuran / 0 - 23 °C

2: 77 percent / NiCl₂*6H₂O; NaBH₄ / tetrahydrofuran; methanol / 0 °C

3: 47 percent / 1,2-dichloro-ethane / 48 h / Heating

With sodium tetrahydroborate; 2,4-(4-phenoxyphenyl)-1,3-dithia-2λ(5),4λ(5)-diphosphetane 2,4-disulfides; nickel dichloride; In tetrahydrofuran; methanol; 1,2-dichloro-ethane; 1: sulfuration / 2: Reduction / 3: Acylation;

DOI:10.1016/S0040-4039(00)01399-X

upstream raw materials:

2-nitroveratraldehyde

Downstream raw materials:

(+/-)-5,8,9,10,11,14-hexahydro-6H-15,16-dimethoxy-7,14-diazacycloundeca[a]indene-7,13-dimethoxy-7,14-diazacycloundeca[a]indene-7,13-dicarboxylic acid 13-methyl ester 7-phenyl ester