Technology Process of (2S)-1-(2-benzyloxyethoxy)dodecan-2-ol
There total 8 articles about (2S)-1-(2-benzyloxyethoxy)dodecan-2-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(2S)-dodecane-1,2-diol;
With
di(n-butyl)tin oxide;
In
methanol; chloroform;
Heating;
benzyl iodoethyl ether;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 18h;
Further stages.;
DOI:10.1021/jo016396u
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 96 percent / H2; NEt3 / 10percent Pd/C / methanol / 24 h / 20 °C
2.1: 94 percent / aq. HCl / methanol / 20 °C
3.1: Bu2SnO / methanol; CHCl3 / 2 h / Heating
3.2: 81 percent / CsF / dimethylformamide / 18 h / 50 °C
With
hydrogenchloride; hydrogen; di(n-butyl)tin oxide; triethylamine;
10percent Pd/C;
In
methanol; chloroform;
DOI:10.1002/chem.200390021
- Guidance literature:
-
Multi-step reaction with 4 steps
2.1: H2 / Pd-C / ethanol
3.1: HCl / methanol
4.1: Bu2SnO / CHCl3; methanol / Heating
4.2: CsF / dimethylformamide
With
hydrogenchloride; hydrogen; di(n-butyl)tin oxide;
palladium on activated charcoal;
In
methanol; ethanol; chloroform;
1.1: Condensation / 2.1: Hydrogenation / 3.1: Ring cleavage / 4.1: Cyclization / 4.2: Substitution;
DOI:10.1002/1521-3773(20000602)39:11<1934::AID-ANIE1934>3.0.CO;2-W
