N-(4-(3-(2,5-dibromophenyl)-5-phenyl-4H-1,2,4-triazol-4-yl)phenyl)-N-phenylbenzenamine

Base Information

• Chemical Name: N-(4-(3-(2,5-dibromophenyl)-5-phenyl-4H-1,2,4-triazol-4-yl)phenyl)-N-phenylbenzenamine
• CAS No.: 1253582-66-9
• Molecular Formula: C₃₂H₂₂Br₂N₄
• Molecular Weight: 622.361
• Mol file: 1253582-66-9.mol

Synonyms:N-(4-(3-(2,5-dibromophenyl)-5-phenyl-4H-1,2,4-triazol-4-yl)phenyl)-N-phenylbenzenamine

Chemical Property of N-(4-(3-(2,5-dibromophenyl)-5-phenyl-4H-1,2,4-triazol-4-yl)phenyl)-N-phenylbenzenamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-(3-(2,5-dibromophenyl)-5-phenyl-4H-1,2,4-triazol-4-yl)phenyl)-N-phenylbenzenamine

There total 8 articles about N-(4-(3-(2,5-dibromophenyl)-5-phenyl-4H-1,2,4-triazol-4-yl)phenyl)-N-phenylbenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

4-aminotriphenylamine (2350-01-8) + 1-((2,5-dibromophenyl)chloromethylene)-2-(chloro(phenyl)methylene)hydrazine (1253582-65-8) → N-(4-(3-(2,5-dibromophenyl)-5-phenyl-4H-1,2,4-triazol-4-yl)phenyl)-N-phenylbenzenamine (1253582-66-9)

Guidance literature:

In N,N-dimethyl-aniline; at 135 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c0jm00707b

Reference yield:

2,5-dibromobenzoic acid methyl ester (57381-43-8) → N-(4-(3-(2,5-dibromophenyl)-5-phenyl-4H-1,2,4-triazol-4-yl)phenyl)-N-phenylbenzenamine (1253582-66-9)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrazine hydrate

2: 1-methyl-pyrrolidin-2-one / 24 h / 45 °C

3: phosphorus pentachloride / toluene / 3 h / 120 °C / Inert atmosphere

4: N,N-dimethyl-aniline / 12 h / 135 °C / Inert atmosphere

With phosphorus pentachloride; hydrazine hydrate; In 1-methyl-pyrrolidin-2-one; N,N-dimethyl-aniline; toluene;

DOI:10.1039/c0jm00707b

Reference yield:

4-Fluoronitrobenzene (350-46-9,178603-76-4) → N-(4-(3-(2,5-dibromophenyl)-5-phenyl-4H-1,2,4-triazol-4-yl)phenyl)-N-phenylbenzenamine (1253582-66-9)

Guidance literature:

Multi-step reaction with 3 steps

2: palladium on activated charcoal; hydrazine hydrate / ethanol

3: N,N-dimethyl-aniline / 12 h / 135 °C / Inert atmosphere

With palladium on activated charcoal; hydrazine hydrate; In ethanol; N,N-dimethyl-aniline;

DOI:10.1039/c0jm00707b

upstream raw materials:

1-(2,5-dibromobenzoyl)-2-benzoylhydrazine

4-aminotriphenylamine

1-((2,5-dibromophenyl)chloromethylene)-2-(chloro(phenyl)methylene)hydrazine

2,5-dibromobenzoic acid methyl ester