(S)-2-(2-{2-[2-(11-Tritylsulfanyl-undecyloxy)-ethoxy]-ethoxy}-acetylamino)-succinamic acid

Base Information

• Chemical Name: (S)-2-(2-{2-[2-(11-Tritylsulfanyl-undecyloxy)-ethoxy]-ethoxy}-acetylamino)-succinamic acid
• CAS No.: 871725-10-9
• Molecular Formula: C₄₀H₅₄N₂O₇S
• Molecular Weight: 706.944
• Mol file: 871725-10-9.mol

Synonyms:(S)-2-(2-{2-[2-(11-Tritylsulfanyl-undecyloxy)-ethoxy]-ethoxy}-acetylamino)-succinamic acid

Chemical Property of (S)-2-(2-{2-[2-(11-Tritylsulfanyl-undecyloxy)-ethoxy]-ethoxy}-acetylamino)-succinamic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-(2-{2-[2-(11-Tritylsulfanyl-undecyloxy)-ethoxy]-ethoxy}-acetylamino)-succinamic acid

There total 2 articles about (S)-2-(2-{2-[2-(11-Tritylsulfanyl-undecyloxy)-ethoxy]-ethoxy}-acetylamino)-succinamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

{2-[2-(11-tritylsulfanyl-undecyloxy)-ethoxy]-ethoxy}-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester + L-asparagine (70-47-3,28088-48-4,7006-34-0) → (S)-2-(2-{2-[2-(11-Tritylsulfanyl-undecyloxy)-ethoxy]-ethoxy}-acetylamino)-succinamic acid (871725-10-9)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; water; at 20 ℃; for 24h;

DOI:10.1021/ol052367k

Reference yield:

{2-[2-(11-tritylsulfanyl-undecyloxy)-ethoxy]-ethoxy}-acetic acid → (S)-2-(2-{2-[2-(11-Tritylsulfanyl-undecyloxy)-ethoxy]-ethoxy}-acetylamino)-succinamic acid (871725-10-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,3-dicyclohexylcarbodiimide / CH₂Cl₂ / 24 h / 20 °C

2: sodium bicarbonate / H₂O; tetrahydrofuran / 24 h / 20 °C

With sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; water;

DOI:10.1021/ol052367k

upstream raw materials:

L-asparagine