(R)-4-([1,4'-bipiperidin]-1'-yl)-2-((2R,3S)-2-((E)-3-⁽¹²³⁾I-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-N-((R)-1-phenylethyl)butanamide

Base Information

• Chemical Name: (R)-4-([1,4'-bipiperidin]-1'-yl)-2-((2R,3S)-2-((E)-3-⁽¹²³⁾I-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-N-((R)-1-phenylethyl)butanamide
• CAS No.: 1361214-58-5
• Molecular Formula: C₄₂H₄₈IN₅O₅
• Molecular Weight: 825.874

Synonyms:(R)-4-([1,4'-bipiperidin]-1'-yl)-2-((2R,3S)-2-((E)-3-⁽¹²³⁾I-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-N-((R)-1-phenylethyl)butanamide

Chemical Property of (R)-4-([1,4'-bipiperidin]-1'-yl)-2-((2R,3S)-2-((E)-3-⁽¹²³⁾I-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-N-((R)-1-phenylethyl)butanamide

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Technology Process of (R)-4-([1,4'-bipiperidin]-1'-yl)-2-((2R,3S)-2-((E)-3-⁽¹²³⁾I-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-N-((R)-1-phenylethyl)butanamide

There total 1 articles about (R)-4-([1,4'-bipiperidin]-1'-yl)-2-((2R,3S)-2-((E)-3-⁽¹²³⁾I-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-N-((R)-1-phenylethyl)butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-4-([1,4'-bipiperidin]-1'-yl)-4-oxo-2-((3S,4R)-2-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)-4-((E)-3-(trimethylstannyl)styryl)azetidin-1-yl)-N-((R)-1-phenylethyl)butanamide (1361214-57-4) → (R)-4-([1,4'-bipiperidin]-1'-yl)-2-((2R,3S)-2-((E)-3-(123)I-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-N-((R)-1-phenylethyl)butanamide (1361214-58-5)

Guidance literature:

With hydrogenchloride; [¹²³I] sodium iodide; chloroamine-T; In ethanol; water; at 20 ℃; for 0.0833333h;

DOI:10.1016/j.bmc.2011.12.013

upstream raw materials:

(R)-4-([1,4'-bipiperidin]-1'-yl)-4-oxo-2-((3S,4R)-2-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)-4-((E)-3-(trimethylstannyl)styryl)azetidin-1-yl)-N-((R)-1-phenylethyl)butanamide

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