<4-oxo-6-<<2-propynyl(3,4,5-trimethoxyphenyl)amino>methyl>-3(4H)-quinazolinyl>methyl 2,2-dimethylpropanoate

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Chemical Name:<4-oxo-6-<<2-propynyl(3,4,5-trimethoxyphenyl)amino>methyl>-3(4H)-quinazolinyl>methyl 2,2-dimethylpropanoate
CAS No.:123685-42-7
Molecular Formula:C₂₇H₃₁N₃O₆
Molecular Weight:493.56
Hs Code.:

Synonyms:<4-oxo-6-<<2-propynyl(3,4,5-trimethoxyphenyl)amino>methyl>-3(4H)-quinazolinyl>methyl 2,2-dimethylpropanoate

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Chemical Property of <4-oxo-6-<<2-propynyl(3,4,5-trimethoxyphenyl)amino>methyl>-3(4H)-quinazolinyl>methyl 2,2-dimethylpropanoate

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Technology Process of <4-oxo-6-<<2-propynyl(3,4,5-trimethoxyphenyl)amino>methyl>-3(4H)-quinazolinyl>methyl 2,2-dimethylpropanoate

There total 3 articles about <4-oxo-6-<<2-propynyl(3,4,5-trimethoxyphenyl)amino>methyl>-3(4H)-quinazolinyl>methyl 2,2-dimethylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 123685-57-4
Prop-2-ynyl-(3,4,5-trimethoxy-phenyl)-amine

: 106585-53-9
<6-(bromomethyl)-4-oxo-3(4H)-quinazolinyl>methyl 2,2-dimethylpropanoate

: 123685-42-7
<4-oxo-6-<<2-propynyl(3,4,5-trimethoxyphenyl)amino>methyl>-3(4H)-quinazolinyl>methyl 2,2-dimethylpropanoate

Guidance literature:: With N,N-dimethyl acetamide; calcium carbonate; for 18h; Ambient temperature;
DOI:10.1021/jm00169a040

Reference yield:

: 24313-88-0
3,4,5-Trimethoxyaniline

: 123685-42-7
<4-oxo-6-<<2-propynyl(3,4,5-trimethoxyphenyl)amino>methyl>-3(4H)-quinazolinyl>methyl 2,2-dimethylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 82.5 percent / N-ethyl-N-(1-methylethyl)-2-propanamine / toluene / 18 h / 90 °C

2: 100 percent / CaCO₃, N,N-dimethylacetamide (DMA) / 18 h / Ambient temperature

With N,N-dimethyl acetamide; N-ethyl-N,N-diisopropylamine; calcium carbonate; In toluene;
DOI:10.1021/jm00169a040