3,3'-Diaminobenzidine tetrahydrochloride dihydrate

Base Information

• Chemical Name: 3,3'-Diaminobenzidine tetrahydrochloride dihydrate
• CAS No.: 868272-85-9
• Molecular Formula: C12H14 N4 . 4 Cl H . x H2 O
• Molecular Weight: 376.15258
• Hs Code.: 29215900
• European Community (EC) Number: 685-525-9,808-580-4
• UNII: Z3KH58591V
• Wikidata: Q27294950
• Mol file: 868272-85-9.mol

Synonyms:167684-17-5;3,3'-Diaminobenzidine tetrahydrochloride dihydrate;(1,1'-Biphenyl)-3,3',4,4'-tetramine tetrahydrochloride dihydrate;UNII-Z3KH58591V;Z3KH58591V;(1,1'-Biphenyl)-3,3',4,4'-tetramine, tetrahydrochloride, dihydrate;(1,1'-Biphenyl)-3,3',4,4'-tetramine, hydrochloride, hydrate (1:4:2);4-(3,4-diaminophenyl)benzene-1,2-diamine;dihydrate;tetrahydrochloride;3,3' Diaminobenzidine Tetrahydrochloride;[1,1'-Biphenyl]-3,3',4,4'-tetramine, hydrochloride, hydrate (1:4:2);3,3-Diaminobenzidine (tetrahydrochloride dihydrate);DAB;868272-85-9;Cambridge id 5140900;MFCD00150106;AKOS015901768;HY-W288940;AS-10374;CS-0333908;3,3'-DIAMINOBENZIDINE TETRAHCL DIHYDRATE;Q27294950;3,3'-DIAMINOBENZIDINE TETRAHYDROCHLORIDE DIHYDRATE [MI]

Chemical Property of 3,3'-Diaminobenzidine tetrahydrochloride dihydrate

Chemical Property:

• Melting Point: 300°C
• PSA: 113.31000
• LogP: 7.15090
• Storage Temp.: Freezer (-20°C)
• Solubility.: H2O: soluble50mg/mL
• Water Solubility.: Soluble at 5%(w/v) in water
• Hydrogen Bond Donor Count: 10
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 396.046737
• Heavy Atom Count: 22
• Complexity: 209

Purity/Quality:

99% ^*data from raw suppliers

3,3′-Diaminobenzidine tetrahydrochloride hydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,T
• Hazard Codes: Xn,T
• Statements: 45-68-36-22
• Safety Statements: 22-24/25-45-53-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1C2=CC(=C(C=C2)N)N)N)N.O.O.Cl.Cl.Cl.Cl
• Recent ClinicalTrials: Study to Evaluate the Effect of SCY-078 on the PK of Dabigatran in Healthy Subjects
• Uses: 3,3'-diaminobenzidine-tetrahydrochloride-dihydrate(DAB) was used as a chromogen, for detecting the antigen-antibody complex. It is one of the most potent marker being used in immunochemistry, mostly at the electron and light microscope levels. It is used as a histological stain for peroxidase activity. Reaction between 3,3'-Diaminobenzidine and peroxidase forms a visible insoluble product. This approach has been used to assay activity of glutamate decarboxylase in rat cerebellar sections and to detect horseradish peroxidase presence on cultured cell surfaces. 3,3′-Diaminobenzidine tetrahydrochloride hydrate can be used in HRP-based assays suitable for immunohistology staining procedures, western blotting, and FISH (fluorescence in situ hybridization). DAB is used in studying epithelial cell apoptosis in the event of early cataracts, and immunohistochemistry protocols of autosomal dominant polycystic kidney disease (PKD).