4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid

Base Information

• Chemical Name: 4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid
• CAS No.: 119348-39-9
• Molecular Formula: C₂₃H₂₆O₆
• Molecular Weight: 398.456
• Mol file: 119348-39-9.mol

Synonyms:4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid

Chemical Property of 4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid

There total 7 articles about 4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid, ethyl ester (119348-37-7) → 4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid (119348-39-9)

Guidance literature:

With sodium hydroxide; In ethanol; for 2h; Heating;

DOI:10.1021/jm00113a014

Reference yield: 61.0%

→ 4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid (119348-39-9)

Guidance literature:

Reference yield:

glutaric anhydride, (108-55-4) → 4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid (119348-39-9)

Guidance literature:

Multi-step reaction with 5 steps

1: 32 percent / CH₂Cl₂ / 3 h

2: 48percent HBr, AcOH / 20 h / Heating

3: AcOH / Heating

4: 96 percent / NaOEt, NaI / ethanol / 72 h

5: 62 percent / 5N NaOH / ethanol / 2 h / Heating

With sodium hydroxide; hydrogen bromide; sodium ethanolate; acetic acid; sodium iodide; In ethanol; dichloromethane;

DOI:10.1021/jm00113a014

upstream raw materials:

4-[(4-Acetyl-3-hydroxy-2-propylphenyl)methoxy]-δ-oxobenzenepentanoic acid, ethyl ester

glutaric anhydride,

5-(4-hydroxy-phenyl)-5-oxo-valeric acid

4-(p-Hydroxybenzoyl)-buttersaeure-ethylester