N-Boc-L-Orn(Cbz)-L-Thr-L-Ala-L-Asn(Trt)-D-Asn(Trt)-D-Leu-L-Thr-D-Leu-D-Ada-OMe

Base Information

Chemical Name:N-Boc-L-Orn(Cbz)-L-Thr-L-Ala-L-Asn(Trt)-D-Asn(Trt)-D-Leu-L-Thr-D-Leu-D-Ada-OMe
CAS No.:1229576-59-3
Molecular Formula:C₉₈H₁₂₈N₁₂O₁₈
Molecular Weight:1762.16
Hs Code.:

Synonyms:N-Boc-L-Orn(Cbz)-L-Thr-L-Ala-L-Asn(Trt)-D-Asn(Trt)-D-Leu-L-Thr-D-Leu-D-Ada-OMe

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Chemical Property of N-Boc-L-Orn(Cbz)-L-Thr-L-Ala-L-Asn(Trt)-D-Asn(Trt)-D-Leu-L-Thr-D-Leu-D-Ada-OMe

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Technology Process of N-Boc-L-Orn(Cbz)-L-Thr-L-Ala-L-Asn(Trt)-D-Asn(Trt)-D-Leu-L-Thr-D-Leu-D-Ada-OMe

There total 1 articles about N-Boc-L-Orn(Cbz)-L-Thr-L-Ala-L-Asn(Trt)-D-Asn(Trt)-D-Leu-L-Thr-D-Leu-D-Ada-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1229576-47-9
C₂₅H₃₈N₄O₉

: 1229576-58-2
C₇₃H₉₂N₈O₁₀

: 1229576-59-3
N-Boc-L-Orn(Cbz)-L-Thr-L-Ala-L-Asn(Trt)-D-Asn(Trt)-D-Leu-L-Thr-D-Leu-D-Ada-OMe

Guidance literature:: C₂₅H₃₈N₄O₉; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; for 0.5h;

C₇₃H₉₂N₈O₁₀; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.tet.2010.03.032

Reference yield:

: 1229576-59-3
N-Boc-L-Orn(Cbz)-L-Thr-L-Ala-L-Asn(Trt)-D-Asn(Trt)-D-Leu-L-Thr-D-Leu-D-Ada-OMe

: C₉₇H₁₂₆N₁₂O₁₈

Guidance literature:: N-Boc-L-Orn(Cbz)-L-Thr-L-Ala-L-Asn(Trt)-D-Asn(Trt)-D-Leu-L-Thr-D-Leu-D-Ada-OMe; With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 0 ℃; for 2h;

With hydrogenchloride; In tetrahydrofuran; water;
DOI:10.1016/j.tet.2010.03.032