1,5-anhydro-3,4,6-tri-O-benzyl-2-deoxy-2-trifluoroacetyl-D-arabino-hex-1-enitol

Base Information

• Chemical Name: 1,5-anhydro-3,4,6-tri-O-benzyl-2-deoxy-2-trifluoroacetyl-D-arabino-hex-1-enitol
• CAS No.: 905283-18-3
• Molecular Formula: C₂₉H₂₇F₃O₅
• Molecular Weight: 512.526
• Mol file: 905283-18-3.mol

Synonyms:1,5-anhydro-3,4,6-tri-O-benzyl-2-deoxy-2-trifluoroacetyl-D-arabino-hex-1-enitol

Chemical Property of 1,5-anhydro-3,4,6-tri-O-benzyl-2-deoxy-2-trifluoroacetyl-D-arabino-hex-1-enitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,5-anhydro-3,4,6-tri-O-benzyl-2-deoxy-2-trifluoroacetyl-D-arabino-hex-1-enitol

There total 1 articles about 1,5-anhydro-3,4,6-tri-O-benzyl-2-deoxy-2-trifluoroacetyl-D-arabino-hex-1-enitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3,4,6-tri-O-benzyl-D-glucal (55628-54-1) + trifluoroacetic anhydride (407-25-0) → 1,5-anhydro-3,4,6-tri-O-benzyl-2-deoxy-2-trifluoroacetyl-D-arabino-hex-1-enitol (905283-18-3)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 96h;

DOI:10.1016/j.carres.2006.01.011

Reference yield: 84.0%

1,5-anhydro-3,4,6-tri-O-benzyl-2-deoxy-2-trifluoroacetyl-D-arabino-hex-1-enitol (905283-18-3) → 4-(1,2,4-tri-O-benzyl-D-arabino-1,2,3,4-tetrahydroxybutyl)-3-trifluoromethyl-1-H-pyrazole

Guidance literature:

With hydrazine hydrate; In ethanol; for 24h; Heating;

DOI:10.1016/j.carres.2006.01.011

Reference yield: 44.0%

1,5-anhydro-3,4,6-tri-O-benzyl-2-deoxy-2-trifluoroacetyl-D-arabino-hex-1-enitol (905283-18-3) + 1,2-diamino-benzene (95-54-5) → 3-(1,2,4-tri-O-benzyl-D-arabino-1,2,3,4-tetrahydroxybutyl)-4-trifluoromethyl-1-H-benzo[b][1,4]diazepine

Guidance literature:

In ethanol; at 20 ℃; for 24h;

DOI:10.1016/j.carres.2006.01.011

upstream raw materials:

3,4,6-tri-O-benzyl-D-glucal

trifluoroacetic anhydride