H-BETA-ALA-AMC TFA

Base Information

• Chemical Name: H-BETA-ALA-AMC TFA
• CAS No.: 201847-54-3
• Molecular Formula: C15H15F3N2O5
• Molecular Weight: 360.29
• Hs Code.: 2932209090
• Mol file: 201847-54-3.mol

Synonyms:BETA-ALANINE 7-AMIDO-4-METHYLCOUMARIN TRIFLUOROACETATE;BETA-ALANINE 7-AMIDO-4-METHYLCOUMARIN TRIFLUOROACETATE SALT;BETA-ALANINE-AMC TFA;H-BETA-ALA-AMC TFA;H-b-Ala-AMC·TFA

Chemical Property of H-BETA-ALA-AMC TFA

Chemical Property:

• PSA: 122.63000
• LogP: 2.79530
• Storage Temp.: -15°C

Purity/Quality:

99% ^*data from raw suppliers

b-Alanine 7-amido-4-methylcoumarin trifluoroacetate salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-BETA-ALA-AMC TFA

There total 2 articles about H-BETA-ALA-AMC TFA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-amino-4-methylcoumarin. (26093-31-2) → C2HF3O2*C13H14N2O3 (201847-54-3)

Guidance literature:

Multi-step reaction with 2 steps

1: trichlorophosphate; pyridine / 1 h / -15 °C

2: dichloromethane / 1 h / 20 °C

With pyridine; trichlorophosphate; In dichloromethane;

DOI:10.1021/acsmedchemlett.9b00569

Reference yield:

C18H22N2O5 + trifluoroacetic acid (76-05-1) → C2HF3O2*C13H14N2O3 (201847-54-3)

Guidance literature:

In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/acsmedchemlett.9b00569

Reference yield:

C2HF3O2*C13H14N2O3 (201847-54-3) → 7-amino-4-methylcoumarin. (26093-31-2)

Guidance literature:

With β-alanyl aminopeptidase; water; In 1-methyl-pyrrolidin-2-one; Enzymatic reaction;

DOI:10.1039/c6ra12875k

upstream raw materials:

trifluoroacetic acid

7-amino-4-methylcoumarin.

Downstream raw materials:

7-amino-4-methylcoumarin.